BACKGROUND: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed …

In dit artikel doen we verslag van een onderzoek naar het vakmanschap van de vmbo-docent in de bovenbouw. Het onderzoek is uitgevoerd in het kader van het innovatiearrangement Professional in Beeld (PiB) waarin drie vmbo-scholen en de lerarenopleiding Archimedes van de Hogeschool Utrecht gewerkt hebben …

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

The aim of this study is to clarify how pre-service teachers perceive mentor teachers' use of mentoring skills. Sixty stimulated-recall interviews were conducted, each in connection with a previously recorded mentoring dialogue. A quantitative analysis showed that six types of mentoring skills appeared …

Introduction In comparison with other European countries, Starbucks is rather new on the Dutch coffee market. The Starbucks experience seems less exploited among the Dutch consumers. This thesis will demonstrate the effect of music and how music can convey the Starbucks experience in order to "engage" …

This study analyses the dilemmas and practical problems in implementing competence-based vocational education through 11 case studies. Schools seem to meet various fundamental issues, but it remains difficult in what way the acquisition and use of a way of knowing and thinking that is based on vocational …

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As all professionals, teacher educators are expected to develop themselves continuously during their working life in order to keep their knowledge and skills up to date. Smith (2003, p203) distinguishes three reasons for teacher educators to develop themselves: 1) to improve the profession (teacher education); …

In September 2009 the department of Engineering of Fontys University of Applied Sciences in the Netherlands has started a pilot honours program for excellent engineering students called PRogram OUstanding Development (PROUD). Aim of this program is to give those engineering students, who have the ambition, …

Over recent years aspects of sustainability have claimed a central role in many countries. As a result research for sustainability has become an important driver for innovation. This paper describes developing a model that supports SMEs in integrating sustainability in their business and innovation processes. In …