Dit rapport is deel I van twee delen waarin de veiligheidsnormen worden onderzocht die van toepassing zijn op waterstoftoepassingen. In deel I wordt ingegaan op de vraag welke normen hoofdzakelijk van toepassing zijn op waterstoftankstations, brandstofcel technologieën en (kleine) waterstof opslag die …

This thesis introduces a cost-effective methodology for estimating tire contact patch forces and moments at wheel centre using axial force measurements from suspension linkages. The primary aim is to reconstruct these dynamic quantities, eliminating reliance on expensive wheel force transducers (WFTs) …

Cyclophosphamide (CPA) is a commonly used alkylating chemotherapeutic drug that targets rapidly dividing cells causing apoptosis by crosslinking DNA. While effective against neoplasms, CPA can also affect healthy immune cells. This study investigated whether a single dose of CPA alters healthy lymphoid …

RNA metabolism is governed by RNA-binding proteins (RBPs), which regulate gene expression in cells, including immune system cells. Cells overcome stressing factors to ensure survival by employing a wide range of mechanisms that mitigate damage and restore homeostasis. One of the mechanisms is the formation …

The gram-positive bacterium Bacillus subtilis is widely used for enzyme production, especially due to its superior protein secretion capacity. In this study, we have investigated how efficient transcriptome analysis can identify general and protein-specific secretion stress. For this, we constructed …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Abstract: Aureobasidium is omnipresent and can be isolated from air, water bodies, soil, wood, and other plant materials, as well as inorganic materials such as rocks and marble. A total of 32 species of this fungal genus have been identified at the level of DNA, of which Aureobasidium pullulans is best …

Alzheimer's disease is a complex neurodegenerative disease and the most prevalent form of dementia. It affects every 14th person after the age of 65, thus making it a serious concern in modern society. Furthermore, currently available treatment is restricted only to symptomatic and is not highly effective. …

The intermittency of renewable energy technologies requires adequate storage technologies. Hydrogen systems consisting of electrolysers, storage tanks, and fuel cells can be implemented as well as batteries. The requirements of the hydrogen purification unit is missing from literature. We measured the …

Abstract Aureobasidium is omnipresent and can be isolated from air, water bodies, soil, wood, and other plant materials, as well as inorganic materials such as rocks and marble. A total of 32 species of this fungal genus have been identified at the level of DNA, of which Aureobasidium pullulans is best …