Phantom limb pain following amputation is highly prevalent as it affects up to 80% of amputees. Many amputees suffer from phantom limb pain for many years and experience major limitations in daily routines and quality of life. Conventional pharmacological interventions often have negative side-effects …

Objective Major issues in children with Marfan syndrome (MFS) are pain, fatigue and joint hypermobility which might influence functional ability. We recently studied these aspects in children with Ehlers-Danlos syndrome hypermobility type (EDS-HT) and hypermobility spectrum disorders (HSD). What can …

Introduction: Neuromuscular diseases (NMD) are a heterogeneous group of acquired or inherited diseases affecting the peripheral nervous system and muscle mass. The consequences of NMD are loss of muscle mass, function, and posture. Loss of muscle mass causes weakness, a decrease in mobility and cardiac …

Background: Marfan syndrome (MFS) is a heritable connective tissue disease caused by a defect in FBN1. The diagnosis is based on the revised Ghent criteria. The main features involve the cardiovascular, musculoskeletal, ophthalmic, pulmonary systems and facial features. Although the clinical manifestations …

The objective of this chapter is to provide clinicians with a clinical model of hEDS and HSD for which treatment can be optimized to the needs of the individual patient. Due to the complexity of the symptom profiles of HSD/hEDS, the international classification of functioning (ICF) will be adopted as …

Inleiding – Bij kinderen met het syndroom van Down (DS) is er sprake van primaire (genetische) en secundaire (niet genetische) problematieken in het mondgebied. De Nederlandse en Duitse richtlijnen zijn verschillend betreft de omgang met deze problematiek. Het doel van dit praktijkgerichte onderzoek …

INTRODUCTION: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low. AIM: This study aimed to determine the prevalence of use of PP in ARDS …