OBJECTIVE: To (1) establish the association of the most common reported symptoms on disability; and (2) study the effectiveness of treatment on disability in patients with Ehlers-Danlos syndrome-hypermobility type (EDS-HT)/hypermobility syndrome (HMS). DATA SOURCES: An electronic search (Medical Subject …

Since Factor H is the main regulator of the complement system, any dysregulation may result in either uncontrolled complement activation or inhibition. Auto-antibodies against Factor H inhibit the protective function of Factor H on host cells, which are now sensitive for complement activation. It is …

This research was conducted on behalf of the education of ‘Management in Healthcare’ at the University of Applied Sciences Leiden. The study of ‘Management in Healthcare’ is an dual education that is intended for working healthcare professionals to a middle manager position in the healthcare and welfare …

Few evidence-based methods for case management in child protection and child welfare are available. That is why Youth Protection Amsterdam Area developed a new method, by integrating their best practices: Intensive Family Case Management (IFCM). Because IFCM was developed in practice, clarity about its …

Common seals (Phoca vitulina) are mostly seen from coastal temperate waters to the Polar Regions. High levels of toxic waste that affect the immune system, fisheries, and new outbreaks of viruses consist of the current threats to the seal populations. The Seal Rehabilitation and Research Centre (SRRC) …

Diminishing motor function is commonly observed in the elderly population and is associated with a wide range of adverse health consequences. Advanced Glycation End products (AGE’s) may contribute to age-related decline in the function of cells and tissues in normal ageing. Although the negative effect …

It is generally assumed that in the countryside of Northeast Netherlands children enter primary school with a language delay. Despite the apparent consensus, unequivocal evidence demonstrating that the number of young children with language delays and the magnitude of these delays is, however, lacking. …

Studies monitoring vitamin D status in athletes are seldom conducted for a period of 12 months or longer, thereby lacking insight into seasonal fluctuations. The objective of the cur-rent study was to identify seasonal changes in total 25-hydroxyvitamin D (25(OH)D) concen-tration throughout the year. …

As smart solutions for healthcare (eHealth) are becoming increasingly widespread, apps and other digital devices may effectively complement various forms of psychotherapy. We point at children and adolescents in psychological therapy as a yet-underserved public for similar solutions. Moreover, a shared …

This bachelor thesis analyses the role of the European Union in the promotion of human rights in Mexico, and its possible efforts to combat human rights violations in this country. It wraps around three main themes. The first one is the current human rights situation in Mexico and the main actors involved …