To validate the model-based 3D dose calculation performed by the COMPASS system, and to evaluate the use of the combination of model-based and measurement-based 3D dose determination for clinical QA purposes.

To quantify the dosimetric accuracy of the COMPASS correction kernel method, and to determine its ability to detect dose delivery errors caused by MLC leaf mis-positioning.

The main objective of this study was to make the transition from a film (2D) based pre-treatment IMRT / IMAT QA into a more efficient and clinical relevant method of verification by reconstructing the dose directly in the patient CT using the COMPASS system. The evaluation of the reconstructed dose includes …

The main goal of this study is to identify knowledge gaps and uncertainties in Quantitative Risk Assessments (QRA) for CO2 pipelines and to assess to what extent those gaps and uncertainties affect the final outcome of the QRA. The impact of methodological choices and uncertain values for input parameters …

Bisphosphonates (BPs) are widely used in the treatment of osteolytic bone disease associated with multiple myeloma, and have been demonstrated to exert antitumor effects both in vitro and in vivo. However, the precise molecular mechanisms involved in the direct antitumor effects of BPs in vitro are not …

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1. An earlier study by our group revealed that the viscosity of faeces from patients with Crohn's disease is significantly lower than that of healthy subjects. This is due to low concentrations of a high-molecular-mass carbohydrate, probably of bacterial origin. The cause of this phenomenon might be …