BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

OBJECTIVES: to test the effects of an intervention involving sensor monitoring-informed occupational therapy on top of a cognitive behavioural treatment (CBT)-based coaching therapy on daily functioning in older patients after hip fracture. DESIGN, SETTING AND PATIENTS: three-armed randomised stepped …

In this study we examine if and how self-evaluated financial knowledge and competences, financial behaviour, financial self-efficacy, and motivation are associated with the severity of financial problems of clients in ‘financial self-management projects’ (Dutch: Thuisadministratie). These projects involve …

This prospective randomized clinical trial evaluated tooth sensitivity and patient satisfaction after the provision of partial ceramic restorations bonded using immediate (IDS) or delayed dentin sealing (DDS) on vital molar teeth through a within-subject comparison study. Between December 2013 and May …

Activity-based work environments are widely adopted; however, research shows mixed findings regarding privacy issues, satisfaction with the work environment, and task performance. To further our understanding, two complementary studies drawing on Person-Environment fit theory were conducted: (1) A field …

OBJECTIVES: The survival and success rate and the quality of survival of partial ceramic restorations bonded employing Immediate (IDS) or Delayed Dentin Sealing (DDS) in vital molar teeth were evaluated in a randomized clinical trial with within-subject comparison study. MATERIALS AND METHODS: 30 patients …

Background Exercise therapy is the cornerstone of knee osteoarthritis (OA) management. In particular muscle strengthening exercise, targeting the characteristic loss of muscle strength present in knee OA, is a key factor for the beneficial effects reported for exercise therapy. The optimal training intensity …

Sadness is now a design problem. The highs and lows of melancholy are coded into social media platforms. After all the clicking, browsing, swiping and liking, all we are left with is the flat and empty aftermath of time lost to the app. Sad by Design offers a critical analysis of the growing social media …

OBJECTIVE: to gain insight into what older adults after hip fracture perceive as most beneficial to their recovery to everyday life. DESIGN: qualitative research approach. SETTING: six skilled nursing facilities. PARTICIPANTS: 19 older community dwelling older adults (aged 65-94), who had recently received …

In deze studie onderzoeken we ondernemers die tegenslagen hebben en de factoren die hiermee te maken hebben. We beschrijven de kenmerken van ondernemers die in de problemen komen en soms zelfs failliet gaan en we combineren de kenmerken met het traject dat deze ondernemers1 hebben gevolgd met hun adviseur. …