RNA metabolism is governed by RNA-binding proteins (RBPs), which regulate gene expression in cells, including immune system cells. Cells overcome stressing factors to ensure survival by employing a wide range of mechanisms that mitigate damage and restore homeostasis. One of the mechanisms is the formation …

Citizen science has demonstrated potential to foster local changes in public health, including physical (in)activity. We used community-engaged citizen science to explore how to improve the exercise-friendliness of a Dutch neighborhood, chosen because it scored below average on important health parameters. …

The gram-positive bacterium Bacillus subtilis is widely used for enzyme production, especially due to its superior protein secretion capacity. In this study, we have investigated how efficient transcriptome analysis can identify general and protein-specific secretion stress. For this, we constructed …

BACKGROUND: Advanced interventions to enhance the mental health literacy (MHL) of educational professionals are now available, though their effectiveness varies, likely due to contextual differences. To adapt these interventions for use in other countries, a systematic and tailored approach is required …

Psychosocial ascriptions in psychosomatic therapy invite the patient not only to confirm and elaborate on their mental feelings, but also make relevant certain therapy goals. Establishing a shared understanding, or “common ground” regarding therapy-relevant topics are appointed by therapist and patient …

This research explored whether machine learning models could predict shifts in participants’ preferences and attitudes towards energy solutions based on behavioural and self-reported engagement data collected during visual educational interventions. Through four sub-questions, the study evaluated how …

In the Europe is a growing interest in interprofessional collaboration (IPC) between childcare, school and family support to offer integrated services for children and their families. However, there is a significant variation in the level of early childhood education and care system integration. In a …

Hard coastal defences along the Dutch–Belgian North Sea coast are nearing the end of their design life and carry significant ecological costs. Salt marsh Nature-Based Solutions (NbS) provide a self-sustaining alternative. However, existing asset-management (AM) standards continue to view them as "nice-to-have" …

This thesis investigates the restoration and structural reinforcement of a historically protected 19th-century residential building on the island of Hydra, Greece. Undertaken within the strict constraints of Greek heritage law (ΦΕΚ 594Δ/1978), the project aims to enhance structural safety and environmental …

This thesis investigates how dynamic capabilities and their underlying microfoundations enable manufacturers to implement digital servitization as a means for circular business model innovation. Digital servitization and circular business model innovation are both gaining traction in the manufacturing …