Introduction: Intractable epilepsy can be treated with the Ketogenic diet (KD). One of the side-effects of the KD is poor bone health. Experience from the Erasmus MC Sophia Children’s Hospital (EMCS) shows that the status of bone mineral density (BMD) is unknown in many cases. This makes it difficult …

The thesis project was devoted to a differentiation of different types of cancer cells checking the effectiveness of the novel anti-leukemia chemicals and exploring whether the best anti-leukemia targets also target bone cancers. The research question of this project is as follows: “How leukemia and …

Young talented athletes that mature have an increased injury risk. Human movement scientist Alien van der Sluis studied soccer players of the talent development program of FC Groningen and tennis players of the talented development program of the Royal Dutch Lawn Tennis Federation (KNLTB). The soccer …

Achtergrond Op de dagbehandeling Hematologie van het Radboudumc is beenmergonderzoek een veelvoorkomende procedure. Ondanks lokale verdoving blijft het voor het merendeel van de patiënten een pijnlijke procedure en resulteert dit in angst en een negatieve ervaring. Verpleegkundigen van de dagbehandeling …

Rationale: The number of obese older adults with diabetes type 2 is increasing worldwide. Weight loss treatment in this group seems beneficial for cardio-metabolic and other health outcomes, but it might reduce muscle mass and bone mineral density (BMD). The association between obesity and BMD is controversial, …

OBJECTIVE: To evaluate the influence of abutment geometry on papillary fill in the esthetic zone in a delayed crown protocol. MATERIALS AND METHODS: Twenty-six subjects received two non-adjacent endosseous implants in the esthetic zone. Functional temporary crowns were installed 17-19 weeks later, using …

Hematological malignancies and treatment with hematopoietic SCT are known to affect patients’ quality of life. The problem profile and care needs of this patient group need clarification, however. This study aimed to assess distress, problems and care needs after allo- or auto-SCT, and to identify risk …

OBJECTIVE: Evaluate clinical outcome of early cyclic intravenous pamidronate treatment in children with moderate-to-severe osteogenesis imperfecta (OI), commenced before three years of age. METHODS: A retrospective review of 17 patients with moderate-to-severe OI. Development, anthropometry, fracture …

Achtergrond: Vooralsnog is er geen behandeling bekend welke genezing van artrose kan geven. Vanuit de literatuur zijn er aanwijzingen dat het zinvol is de biomechanische toestand van het artrotische gewricht te herstellen. Met gewrichtsdistractie bij knie- en enkelartrose wordt gepoogd, door middel van …