OBJECTIVE: To determine whether aerobic capacity is normal in boys with different types of hemophilia compared with healthy peers and whether the level of aerobic capacity correlates with the amount of physical activity, joint health status, muscle strength, and anthropometrics. STUDY DESIGN: 47 patients …

OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with …

Chapter 1 provides a general overview of the interstate relationship before World War I until World War II. Chapter 2 treats the UN Security Council. The first part describes its formation, and composition. Part two describes the legitimacy of the permanent five. It explains why these UN member states …

Bisphosphonates (BPs) are widely used in the treatment of osteolytic bone disease associated with multiple myeloma, and have been demonstrated to exert antitumor effects both in vitro and in vivo. However, the precise molecular mechanisms involved in the direct antitumor effects of BPs in vitro are not …

Organisaties vertrouwen erop goedkopere diensten te kunnen leveren met een betere service door onderdelen van bestaande bedrijfsfuncties te concentreren in een Shared Service Center. Die projecten zijn echter zeer complex en vaak mislukken ze, omdat (tegen)krachten ontstaan als gevolg van een verschuiving …