Introduction: In the Netherlands, Diagnostic Reference Levels (DRLs) have not been based on a national survey as proposed by ICRP. Instead, local exposure data, expert judgment and the international scientific literature were used as sources. This study investigated whether the current DRLs are reasonable …

BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

In light of recent developments of the onboard ballast water treatment, WMR has developed a new protocol for the assessment of ecotoxicological effects and aims to use it as a standardised test. This study looks into the validation of this short-chronic ELS fish toxicity test, by use of the embryonic …

Op de angiografie worden interventies van de bloedvaten uitgevoerd, waarbij de medewerkers worden blootgesteld aan straling. In de recente wetgeving is de dosis voor de ooglens bijgesteld van 150 mSv naar 20 mSv per jaar. In deze studie is onderzocht wat de ontvangen ooglensdosis van de interventie radiologen …

Het doel van dit praktijkgericht onderzoek is een advies geven aan het OK-personeel in het Medisch Centrum Leeuwarden, zodat zo stralingshygiënisch als praktischer wijs mogelijk gewerkt kan worden bij werkzaamheden met de mini C-boog bij hand-/polschirurgie. Tijdens acht ingrepen met de mini C-boog is …

Objective: To evaluate the delivery, acceptance and experiences regarding a traditional and teletreatment approach to mirror therapy as delivered in a randomized controlled trial. Design: Mixed methods, prospective study. Setting: Rehabilitation centres, hospital and private practices. Subjects: Adult …

Epithelial ovarian cancer (EOC) has a poor prognosis in advanced stages. High-dose chemotherapy (HDC) was pursued in the 1990s but was not found to improve survival of patients with EOC in larger studies. Many patients with cancer use Viscum album extracts (VAE). Also called European mistletoe, Viscum …

OBJECTIVES: To compare low contrast detail (LCD) detectability and radiation dose for routine paediatric chest X-ray (CXR) imaging protocols among various hospitals. METHODS: CDRAD 2.0 phantom and medical grade polymethyl methacrylate (PMMA) slabs were used to simulate the chest region of four different …

Lasiocarpine and riddelliine are pyrrolizidine alkaloids (PAs) known to cause liver toxicity. The aim of this study was to predict the inter-species and inter-ethnic human differences in acute liver toxicity of lasiocarpine and riddelliine using physiologically based kinetic (PBK) modelling based reverse …

Van der Burg's study delved into the potential connection between overall survival and patient characteristics, along with radiation dose to the body in lung cancer patients undergoing various treatment schedules. In conclusion, patient characteristics and radiomics data exhibit predictive values for …