Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

What happens if there is a business that is strictly online, is available in multiple countries, therefore facing more competition, while having only one location for their office? This is how YourSurprise operates. Active in 28 countries, delivering almost to the whole world and having multiple websites. …

Dit onderzoek wordt op een kwalitatieve manier uitgevoerd om te achterhalen hoe de kwaliteit van arbeid een rol speelt om medewerkers te kunnen behouden, in dit geval binnen de organisatie Ennatuurlijk. Hierbij worden de 4 A’s, inhoud, verhoudingen, omstandigheden en voorwaarden, bevraagd bij medewerkers …

De hoofdvraag van het onderzoek is: “Welke factoren hebben invloed op de motivatie van de leerlingen uit de bovenbouw havo en vwo van het Jan van Brabant College?”. Om antwoord te kunnen geven op deze hoofdvraag, zijn drie deelvragen geformuleerd. De deelvragen zijn als volgt: • Welke rol heeft verbondenheid …

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

Background Early Childhood Education and Care (ECEC) teachers at urban preschools are potential key figures to promote healthy behaviours in disadvantaged young children and to engage parents in lifestyle-related topics. An ECEC teacher-parent partnership regarding healthy behaviours may support parents …

Aim: To investigate the effects of exercise on salivary concentrations of inflammatory markers by analyzing a panel of 25 inflammatory markers in subjects who had participated in bicycle ergometer tests varying in workload and hydration status. Methods: Fifteen healthy young men (20-35 years) had performed …

This research examines the effects of company expansion on its employees, when there is no indication of further expanding the team. The sales team at Sircle Collection is becoming frustrated as there is no communication of how this expansion will effect their responsibilities. Some employees are currently …

Abstract Background Dermoscopy is known to increase the diagnostic accuracy of pigmented skin lesions (PSLs) when used by trained professionals. The effect of dermoscopy training on the diagnostic ability of dermal therapists (DTs) has not been studied so far. Objectives This study aimed to investigate …