Already for many centuries the only hill castle of the Netherlands is kept in the present picturesque, yet ruined state. Its fate was sealed by historic twists, which brought the willful loss of its strategic status. Today the site is protected by the monumental ruins and is conserved as part of the …

Drumul Taberei, a postwar modernist district of Bucharest, has a share in Romanian urban history with a start as a socialist high-rise utopia, subsequent densification in the ample green spaces under political repression and a downfall due to seismic threats. Through research the cultural and architectural …

Postwar reconstruction nowadays has become a deeply researched subject, not only to meet the need for rebuilding in former war zones, but also to meet the requirements of the homecoming after people’s return. This project, situated in the Saltivka micro district in Kharkiv, Ukraine, follows a number …

Within the Netherlands, historic estates form an important part of the Dutch landscape with many sites dating back to the seventeenth and eighteenth century. In recent years, there has been increased attention and interest to stimulate the development and revival of historic estate kitchen gardens in …

‘Reshape Your Commons’ transposes the call for a ludic living environment into the zone of urban renewal along the IJ in Amsterdam-Noord, stretching from the Eye Institute towards the NSDM district. The place which once counted as a hotspot for alternative urban culture is now diagnosed with stagnated …

Hof van den Houte’ is the new name for a shopping and housing district in the present heart of Etten-Leur, once the site of a castle by the same name between the villages Etten and Leur. The site was still an open field when a modern freestanding shopping mall was built in the 1960s to serve the growing …

Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

Wilms tumour suppressor gene (WT1) is essential for normal development of a kidney, it was also discovered as a major controller of mesenchymal-epithelial balance in general development of organs. In this project we use Wt1 and its role in the mesenchymal-epithelial balance to study the mechanism of …

One of the first questions that a company most of the time puts in before investing in a workplace vitality trajectory is what the return or effect is of a workplace vitality trajectory. They want to know what it really gives the organization in return if they invest in vitality, in order to decide whether …

In the Netherlands, the position of the city center is transitioning from a place-to-buy to a place-to-be. This means that the city center is changing from a place where people come to shop, to a place where people come to meet and experience. This shift causes Municipalities to reevaluate the position …