Hyperhomocysteinemia is a risk factor for cardiovascular disease, neurological disorders, and bone abnormalities. The key enzyme in homocysteine metabolism, cystathionine-β-synthase (CBS) is recognized as a target for new homocysteine-lowering therapies including enzyme replacement and gene therapy. …

Einleitung: In der Ergotherapie kommt es zu langen Wartelisten, die unter anderem auf die COVID-19-Pandemie und das erhöhte Klient*innenaufkommen zurückzuführen sind. Der Umgang mit Wartelisten ist bislang unerforscht. Deshalb soll untersucht werden, wie der Umgang in deutschen ambulanten ergotherapeutischen …

Purpose: Facing the COVID-19 pandemic, police officers are confronted with various novel challenges, which might place additional strain on officers. This mixed-method study investigated officers' strain over a three-month-period after the lockdown. Methods: In an online survey, 2567 police officers …

On duty, police officers are exposed to a variety of acute, threatening stress situations and organizational demands. In line with the allostatic load model, the resulting acute and chronic stress might have tremendous consequences for police officers’ work performance and psychological and physical …

Background: The heat shock protein (HSP) inducer, geranylgeranylacetone (GGA), was previously found to protect against atrial fibrillation (AF) remodeling in experimental model systems. Clinical application of GGA in AF is limited, due to low systemic concentrations owing to the hydrophobic character …

This CIENS-report sums up the main findings from the project “Cultural heritage and water management in urban planning” (Urban WATCH), financed by the Research Council of Norway through the MILJØ2015 programme, and cofunded by the Directorate for Cultural Heritage in Norway (Riksantikvaren) and the Geological …

Since the dawn of advertising in the Netherlands there have been much changes. Advertising has become an essential tool for any type of organization (Rakker, 2009). Nowadays, grasping the attention of an audience is becoming more and more difficult (Libbenga, 2013). Mark Jetten (2014) said “We barely …

According to the "membrane sensor" hypothesis, the membrane's physical properties and microdomain organization play an initiating role in the heat shock response. Clinical conditions such as cancer, diabetes and neurodegenerative diseases are all coupled with specific changes in the physical state and …

Atrial fibrillation (AF) is the most common clinical tachyarrhythmia associated with significant morbidity and mortality and is expected to affect approximately 30 million North Americans and Europeans by 2050. AF is a persistent disease, caused by progressive, often age-related, derailment of proteostasis …