Nicotine is a well-known and highly addictive substance with complex effects on cognition, anxiety, and neurophysiology. Despite its short-term anxiolytic effects, this drug often exacerbates anxiety symptoms. It disrupts emotional regulation through its impact on the central nucleus of the amygdala …

The high prevalence rate of tobacco consumption among teenage school students has become a global issue with profound implications for their developmental trajectory. Research conducted at drug-abuse hot-spots as a proximal factor related to tobacco use has been limited. Therefore, the present study …

International students form a large subgroup of university college students in The Netherlands. Because little is known about substance use in this group, we investigated substance use and the perceptions thereof in a sample of 515 international students in a Dutch university city using an online survey. …

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

Voor veel jongeren in het hoger onderwijs (hbo en wo) is de studententijd een periode waarin regelmatig (veel) alcohol wordt gedronken. Daarnaast komt er in deze fase ook vaak voor het eerst drugsgebruik ter sprake (Trimbos-instituut, 2021). Dit middelengebruik brengt verscheidene risico’s met zich mee. …

Drug consumption estimates are of relevance because of public health effects as well as associated criminal activities. Wastewater analysis of drug residues enables the estimation of drug consumption and drug markets. Short-term and long-term trends of cocaine, MDMA (ecstasy), amphetamine (speed) and …

Cannabis is commonly characterized as the most normalized illicit drug. However, it remains a prohibited substance in most parts of the world, including Europe, and users can still be subject to stigmatization. The objective of this study is to assess to what extent and how cannabis users in different …

The aim of this cross-sectional study is (1) to describe the socio-demographic characteristics of students with relatives with problematic substance use and to examine differences between students with and without relatives with problematic substance use in (2) health, (3) substance use and (4) study …

The last decades have seen an increase in the use of illicit recreational drugs. In this article we take a detailed look at the current state of normalisation of the three most popular illicit recreational drugs among Dutch university students in the Netherlands (MDMA/Ecstasy, cocaine and amphetamine) …