RNA metabolism is governed by RNA-binding proteins (RBPs), which regulate gene expression in cells, including immune system cells. Cells overcome stressing factors to ensure survival by employing a wide range of mechanisms that mitigate damage and restore homeostasis. One of the mechanisms is the formation …

Cardiovascular diseases (CVDs) are by far the leading cause of death due to non communicable diseases in the world. The development of CVDs in many cases is caused by atherosclerosis. In atherosclerosis, plaques in blood vessels are formed by the excessive accumulation of lipids in the endothelial lining. …

SMPD4 is a neutral sphingomyelinase that plays an important role in sphingolipid metabolism. Sphingolipids are a family of lipid molecules abundantly present in the brain where they play an important role in the brain development and function due to their essential cellular role as structural components …

A theoretical and cultural framework, derived from Japanese sources and work by Lebbeus Woods, leads to a vision and design promoting a neo-metabolism, an architecture subjected to its users. De-territorialization and translucency join in creating a collective environment with private units, assembled …

From the thesis: "Summary Metabolic diseases that are characterized by a disturbance in energy balance because of feeding behavior, such as obesity and anorexia are known to be a world-wide problem. A better understanding in central regulation of energy intake and metabolism could give more insight in …