Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Groene schoolpleinen bieden unieke kansen voor onderwijs, maar er is nog veel behoefte aan voorbeelden voor het dagelijks gebruik. In dit onderzoek hebben we gekeken hoe onderwijs op groene schoolpleinen in Nederland wordt gegeven. We onderzochten welke vakken op groene schoolpleinen worden gegeven, …

A historic focus of equine research has been on the time that equids are actively trained, exercised, or handled by humans. Furthermore, research focusing on equine management has mostly been restricted to veterinary interventions aimed at promoting physical …

The problem with investments in digital technology arise when much wanted and needed small companies and entrepreneurs have to invest in costly device the benefits of which are largely unforeseen, or unpredictable. An example of this is the use of 3D whole garment knitwear machines, there not only the …

Factors associated with physical activity among patients eligible for cardiac rehabilitation: a qualitative studyTo optimize recovery following a cardiac event, Cardiac Rehabilitation (CR) is often recommended. Currently, CR is mostly offered as a standardized program, consisting of exercise therapy, …

The construction and demolition is a resource intensive sector, with Construction and Demolition Wastes (CDWs) considered as the largest waste streams accounting for 374 million tonnes in Europe. Although the 70% target for material recovery of CDWs set in the European Union Waste Directive Framework …

BACKGROUND: The mainstay of colorectal cancer care is surgical resection, which carries a significant risk of complications. Efforts to improve outcomes have recently focused on intensive multimodal prehabilitation programs to better prepare patients for surgery, which make the perioperative process …

REducing Delay through edUcation on eXacerbations (REDUX) shows promise in reducing exacerbation recognition and action delays for chronic lung diseases in the Netherlands. However, factors influencing its successful implementation in China remain unclear. To identify the perceived factors influencing …

Unraveling the numerous factors that drive phenotypic variation in trait expression among animals has long presented a significant challenge. Whereas traits like growth and adult size are often heritable and are passed on from one generation to the next, these can be significantly affected by the quality …

Wineries are not new in the Netherlands, but they still are mostly small scale and for this reason have separate locations for growing the vines and processing the grapes. This design project outlines a different scenario, where vacant agricultural plots are combined into a large whole and can support …