Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …

Purpose: Exercise therapy is an effective intervention in a variety of chronic diseases. The prescription of exercise therapy is usually directed toward an index disease. The presence of comorbidity may require adaptations to the exercise program as intended for the index disease. This paper aims to …

The culture of fear seems to be increasingly embedded in today’s society, especially on highly social unequal countries, such as Brazil. The rise of the “condomínios fechados” (gated communities) on recent years expose how this fear shapes our cities. People are sold by the idea of isolating themselves …

Purpose: Instability of the knee joint is reported by a majority (>65%) of patients with knee osteoarthritis (KOA) and is hypothesized to play a crucial role in the initiation and progression of KOA. A generally accepted objective metric of knee joint stability is lacking, making development of diagnostics …

This study explores how 33 student teachers’ reflections during 106 ‘bumpy moments’ while in an international student teaching internship reveal their professional beliefs, and how the moments make the student teachers reflect upon their subjective educational theories. Student teachers described four …

The wine industry in the Czech Republic is a main economic sector, which is verified since the country entered the Europe in 2004. It has a strategic logistic position for exporting to Central and Eastern Europe and has the widest network of hypermarkets and supermarkets in Europe. On another hand, independent …

Abstract Background: Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing type-2 diabetes and readmission. Treatment of AiWG is currently challenging, …

Background: There is increasing interest in the role that technology can play in improving the vitality of knowledge workers. A promising and widely adopted strategy to attain this goal is to reduce sedentary behavior (SB) and increase physical activity (PA). In this paper, we review the state-of-the-art …

Vietnam, a country with great opportunities in the alcohol industry, especially in the wine sector, is developing; and Vietnamese attitudes are changing. The industry has the possibility of participating in social development now and in the future. However, the wine industry has some issues and firstly …

The dynamic nature of daylight and occupant's position can cause some issues such as heat gains and visual discomfort, which need to be controlled in real-time operation. Responsive facades have been pervasively used for preventing daylight glare and meeting daylight performance requirements. However, …