Protein kinases function as pivotal regulators in biological events, governing essential cellular processes through the transfer of phosphate groups from ATP molecules to substrates. Dysregulation of kinase activity is frequently associated with cancer, ocasionally arising from chromosomal translocation …

Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we use an integrative approach to assess human skeletal muscle metabolism during bed rest and provide a multi-system …

INTRODUCTION: There is a growing interest in the involvement of family members of older patients with cancer in decision-making processes. The aim of this study is to identify how and to what extent family members, together with patients and physicians, are involved in triadic decision-making processes …

Purpose: Employer branding (EB) has become a powerful tool for organizations to attract employees. Recruitment communication ideally reveals the image that companies want to portray to potential employees to attract talents with the right skills and competences for the organization. This study explores …

While digitalisation requires facilities management (FM) organisations to change at an increasing rate, little is known about the mechanisms that create ownership and enable individuals to implement changes in everyday FM practice. In this study, these mechanisms are explored from a stewardship perspective. …

Detection and identification of body fluids are crucial aspects of forensic investigations, aiding in crime scene reconstructions and providing important leads. Although many methods have been developed for these purposes, no method is currently in use in the forensic field that allows rapid, non-contact …

Background: INTELLiVENT-adaptive support ventilation (ASV) is an automated closed-loop mode of invasive ventilation for use in critically ill patients. INTELLiVENT-ASV automatically adjusts, without the intervention of the caregiver, ventilator settings to achieve the lowest work and force of breathing. …

Producing evidence that can be used in court is a central goal of criminal investigations. Forensic science focuses with considerable success on the production of pieces of evidence from specific sources. However, less is known about how a team of investigating police officers progressively produces …

Since late 2020, all district courts and courts of appeal in the Netherlands have internal forensic support in the form of “forensic advisers.” This position was created in 2012 and resulted from the efforts made to expand knowledge of the forensic sciences within the inquisitorial Dutch criminal justice …

This study presents a detailed buckling analysis of laminated composites reinforced by multi-walled carbon nanotube (MWCNT) inclusions using a multiscale computational framework. It combines multiple analytical and computational techniques to assess the performance of these composites under varying hygro-thermo-mechanical …