When risky child and family circumstances cannot be resolved at home, (temporary) 24-h out-of-home placement of the child may be an alternative strategy. To identify specific placement risks and needs, care professionals must have information about the child and his or her family, care history, and social-cultural …

Surgery aims to improve a patient’s medical condition. However, surgery is a major life event with the risk of negative consequences, like peri- and postoperative complications, prolonged hospitalization and delayed recovery of physical functioning. One of the major common side effects, functional …

PURPOSE: To explore rehabilitation professionals' opinions about the influence and the pathways of injury compensation (IC) on health and disability in patients with whiplash associated disorder (WAD). METHODS: Semi-structured interviews were performed among a purposeful selected sample of Dutch expert-professionals …

Biogas produced through Anaerobic Digestion can be seen as a flexible and storable energy carrier. However, the environmental sustainability and efficiency of biogas production is not fully understood. Within this article the use, operation, structure, validation, and results of a model for the environmental …

The energy efficiency and sustainability of an anaerobic green gas production pathway was evaluated, taking into account five biomass feedstocks, optimization of the green gas production pathway, replacement of current waste management pathways by mitigation, and transport of the feedstocks. Sustainability …

Synthetic glucocorticoids are potent anti-inflammatory drugs but show dose-dependent metabolic side effects such as the development of insulin resistance and obesity. The precise mechanisms involved in these glucocorticoid-induced side effects, and especially the participation of adipose tissue in this …

Heme is a suggested limiting factor in peroxidase production by Aspergillus spp., which are well-known suitable hosts for heterologous protein production. In this study, the role of genes coding for coproporphyrinogen III oxidase (hemF) and ferrochelatase (hemH) was analyzed by means of deletion and …

Swarm planning is a theory and practical approach to deal with uncertain futures. By anticipating scenarios such as a ‘post-carbon’ world and a ‘pre-adaptive’ landscape, it offers an alternative pathway to prepare for medium-term incremental and step changes. The focus is on the regional scale with a …

BACKGROUND: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed …

In this chapter it is argued that fundamental change in society is required, because environmental problems are serious and ask for a factor 10 or more shift in society, the resilience approach (as outlined in Chap. 2 ) implies change to higher resilience systems and current spatial planning is unable …