We tested the hypothesis that in human ageing, a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance, and altered mitochondrial function. Frailty was assessed according to the Fried criteria and physical performance was determined by 400 m walk …

Frailty is the most common manifestation of serious health issues in the world, and it is becoming more prevalent worldwide as the aging population grows. Changes that occur in an individual during the aging process have physical, psychological, social, and environmental aspects that make an individual …

The four previous articles in this series addressed the myths and facts surrounding lipoedema. We have shown that there is no scientific evidence at all for the key statements made about lipoedema-which are published time and time again. The main result of this misunderstanding of lipoedema is a therapeutic …

BACKGROUND: Coach2Move is a personalized treatment strategy by physical therapists to elicit physical activity in community-dwelling older adults with mobility problems. OBJECTIVE: The primary objective of this study is to assess the effectiveness and cost-effectiveness of the implementation of Coach2Move …

Purpose: To investigate the prevalence of multidimensional frailty in older people with hypertension and to examine a possible relationship of general obesity and abdominal obesity to frailty in older people with hypertension. Patients and Methods: A sample of 995 community-dwelling older people with …

Objective: The Tilburg Frailty Indicator (TFI) is a self-report user-friendly questionnaire for assessing multidimensional frailty among community-dwelling older people. The main aim of this study is to re-evaluate the validity of the TFI, both cross-sectionally and longitudinally, focusing on the predictive …

Objectives: The purpose of this systematic review and meta-analysis was to summarize the prevalence of, and association between, physical frailty or sarcopenia and malnutrition in older hospitalized adults. Design: A systematic literature search was performed in 10 databases. Setting and Participants: …

Op 8 januari 2020 verdedigde ik mijn proef - schrift bij de Rijksuniversiteit Groningen. Het proefschrift richt zich op het vergroten van inzicht in de aard en de omvang van potentiële complicaties na het toepassen van manueeltherapeutische handelingen aan de cervicale wervelkolom bij mensen met nekpijn …

Background: Frailty is considered highly prevalent in older age. Frailty causes a high risk of falls, disability, hospitalization, and mortality. This eventually might be the turning-point for older patients to shift from independent living to assisted living. Poor nutritional status might be an important …