Caenorhabditis elegans is an invertebrate model organism used in many areas of biology including developmental biology and the identification of molecular mechanisms and pathways. However, several experimental approaches require large quantities of worms, which is limiting and time-consuming. We present …

Lesson study is a professional development program that combines teachers’ active engagement and observation of teachers’ lessons. During a lesson study teachers collaborate in a lesson study team. In this study, four participating research supervisors have developed, taught, evaluated and redesigned …

Reporting of research findings is often selective. This threatens the validity of the published body of knowledge if the decision to report depends on the nature of the results. The evidence derived from studies on causes and mechanisms underlying selective reporting may help to avoid or reduce reporting …

The need to reduce carbon emissions calls for more use of renewable generation, particularly distributed resources. The intermittency of renewable generation, and concerns about energy security, require us to become more independent of central grid operation by use of local or regional (micro-grid) electricity …

The 2018 IPCC Special Report on Global Warming of 1.5 °C once again highlighted (and with increased urgency) the benefits of immediate, extreme decarbonisation efforts in order to minimise the negative impacts of climate change. Achieving such demanding global targets requires concerted national, subnational, …

Introduction: The implementation of oncology care pathways that standardize organizational procedures has improved cancer care in recent years. However, the involvement of “authentic” patients and caregivers in quality improvement of these predetermined pathways is in its infancy, especially the scholarly …

Trends and driving forces around us are moving fast in multiple directions. Technical developments in the fields of circular economy, internet of things, bio-based products, robotics, energy and materials are influencing and reshaping our transactional and contextual environment. To create integrated …

Now, that the European cities are overcoming the recent economic challenges, they accelerate the development of major housingschemes to accommodate their growing urban population. Amsterdam for instance, sets out to construct 50,000 new homes by 2025. Parallel to this, the City Council presented a new …

Background Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating …