Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

The shallow peat lake system the Reeuwijkse Plassen are part of the Water Framework Directive. The Regional Water Authority has been attempting to improve the water quality and ecological status of the lakes over the last two decades. After a series of measures the lakes however still score quite poorly. …

Airborne pollen monitoring is of global socio-economic importance as it provides information on presence and prevalence of allergenic pollen in ambient air. Traditionally, this task has been performed by microscopic investigation, but novel techniques are being developed to automate this process. Among …

"Over two-thirds (67%) of global office workers feel like they are constantly repeating the same tasks over and over again, according to a recent survey performed by a leading enterprise automation software company. The employees (specifically the starters and interns) of Cushman & Wakefield in Prague …

Ever since lake Volkerak got its status as a partially closed-off lake in the late ‘80s, excessive (cyanobacterial) algae blooms in the summer period have been a consistently occurring problem. This research aims to investigate the location-specific effectiveness of wetlands and floodplains in nutrient …

Salt marshes are known to be an important habitat type for numerous species of fish. As fish stocks are pressured around the world, providing them with suitable habitat is very important. Through managed realignments or tidal restoration, intertidal salt marshes are created or restored. Which fish use …

Respiratory pathogens like Streptococcus pneumoniae can cause severe pneumonia. Nonetheless, mechanically ventilated intensive care patients, who have a high risk of contracting pneumonia, rarely develop pneumococcal pneumonia. Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, …

At this moment, charging your electric vehicle is common good, however smart charging is still a novelty in the developing phase with many unknowns. A smart charging system monitors, manages and restricts the charging process to optimize energy consumption. The need for, and advantages of smart charging …

The present study investigated the abundance and distribution of protected seagrass associated species within the introduced Halophila stipulacea meadows on St. Eustatius. These species are the queen conch, Caribbean spiny lobster, slender seahorse, green turtle and several species of grouper (Epinephelus …

The natural value of Dutch sandy beaches has been declining for decades. These relatively unstable, low nutritious, wave-washed environments lack the primary producers that represent the base of the food web. Thus, the sandy beach food web relies almost entirely on nutrient influx of other systems. Beside …