Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Student success is a critically important concept in educational assessment and research, yet a comprehensive synthesis of its defining elements remains absent. To address this gap, a scoping review was conducted, identifying 274 peer-reviewed studies published between 2011 and 2022. From these studies, …

To reduce greenhouse gas emissions, countries around the world are pursuing electrification policies. In residential areas, electrification will increase electricity supply and demand, which is expected to increase grid congestion at a faster rate than grids can be reinforced. Battery energy storage …

A novel synthetic approach to 2,6-bis(acrylamido)pyridine (BAAPy) has been developed, producing a dual-function monomer able to self-crosslink while providing functional binding sites through its amide and pyridine groups. The monomer's structure and purity were confirmed through NMR, FTIR, and HPLC …

Achtergrond Objectieve beoordeling van pijngerelateerd gedrag is cruciaal bij volwassenen met een ernstige verstandelijke en meervoudige beperking. Er is momenteel geen gestandaardiseerd instrument voor pijnobservatie beschikbaar dat specifiek op deze doelgroep is gericht. In een eerder onderzoek zijn …

This study presents an automated method for detecting and measuring the apex head thickness of tomato plants, a critical phenotypic trait associated with plant health, fruit development, and yield forecasting. Due to the apex's sensitivity to physical contact, non-invasive monitoring is essential. This …

Multi-layer cell constructs produced in vitro are an innovative treatment option to support the growing demand for therapy in regenerative medicine. Our research introduces a novel construct integrating organ-derived decellularised extracellular matrix (dECM) hydrogels and 3D-printed biodegradable polymer …

BACKGROUND: Communicative participation is the most important outcome of speech and language therapy, but there are no measurement instruments for children, adolescents, and young adults. This paper describes the development of MyCommunication-Youth: an item bank to measure self-reported communicative …

In daily interaction with horses, humans primarily rely on facial expression as a non-verbal equine cue for emotional information. Difficulties in correctly recognizing these signals might arise due to the species-specificity of facial cues, possibly leading to diminished equine welfare and health. This …

Toeleverende bedrijven in de Brainport regio zijn veelal te typeren als high mix low volume (HMLV) productieomgevingen. Deze bedrijven kenmerken zich door een breed aanbod aan mogelijke producten (grote variëteit in producten), die veelal in lage volumes geproduceerd worden. Vaak zijn dit klantspecifieke …