HBO Kennisbank

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Zocht je misschien: moderated?

Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy

Kierkels, Roel G J; Visser, Ruurd; Bijl, Hendrik P; Langendijk, Johannes A; van 't Veld, Aart A; Steenbakkers, Roel J H M; Korevaar, Erik W

OBJECTIVES: To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system. METHODS: Twenty HNC patients were enrolled in this in-silico comparative planning …

2015-04-12AlgemeenArtikel

Research article – A comparison of Sinogram Affirmed Iterative Reconstruction and filtered back projection on image quality and dose reduction in paediatric head CT: a phantom study

Bakker, Astrid; de Lange, René; Ahmed, Abdulfatah; Garcia, André; Tomkinson, David; Salamin, Julie; Buyvidovich, Sergey A.; Sohrabi, Tina; Dominguez, Alexandre; Campeanu, Cosmin

Background: Computed tomography (CT) is one of the most used modalities for diagnostics in paediatric populations, which is a concern as it also delivers a high patient dose. Research has focused on developing computer algorithms that provide better image quality at lower dose. The iterative reconstruction …

2015AlgemeenConferentiebijdrage

Evaluation of DVH-based treatment plan verification in addition to gamma passing rates for head and neck IMRT

Visser, Ruurd; Wauben, David J.L.; de Groot, Martijn; Steenbakkers, Roel J.H.M.; Godart, Jeremy; van 't Veld, Aart A.; Langendijk, Johannes A.; Korevaar, Erik W.; Bijl, Hendrik P

Background and purpose: Treatment plan verification of intensity modulated radiotherapy (IMRT) is generally performed with the gamma index (GI) evaluation method, which is difficult to extrapolate to clinical implications. Incorporating Dose Volume Histogram (DVH) information can compensate for this. …

2014-09-01AlgemeenArtikel

The characterisation of a syntethic single crystal diamond detector

Wouter Verbeek (Student); A.M. Notenboom (Begeleider)

When treating cancer by radiation therapy it is always the goal to irradiate the tumour as much as possible and to spare the healthy tissue around it. For this a new type of radiation therapy called Volumetric Modulated ARC Therapy (VMAT) has been developed. During VMAT treatment the radiation machine …

2014Gezondheid; …Bachelor

Efficient and reliable 3D dose quality assurance for IMRT by combining independent dose calculations with measurements

Visser, Ruurd; Wauben, D.J.L.; de Groot, Martijn; Godart, Jeremy; Langendijk, Johannes A.; van't Veld, A.A.; Korevaar, Erik W.

PURPOSE: Advanced radiotherapy treatments require appropriate quality assurance (QA) to verify 3D dose distributions. Moreover, increase in patient numbers demand efficient QA-methods. In this study, a time efficient method that combines model-based QA and measurement-based QA was developed; i.e., the …

2013-01-18AlgemeenArtikel

ss-TEA

umc, radboud; Fleuren, Wilco W M; Verhoeven, Stefan; van den Beld, Sven; Alkema, Wynand; de Vlieg, Jacob; Klomp, Jan P G

Background: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinformatics …

2011-08-10AlgemeenArtikel

Sequentially delivered boots plans are superior to simultaneously delivered plans in head and neck cancer when the boost volume is located further away from the parotid glands

Anke van Mourik; Emmy Lamers-Kuijper (Lid Lectoraat); Wilma Heemsbergen; Coen Rasch

Purpose: to find parameters that predict which head and neck patients benefit from a sequentially delivered boost treatment plan compared to a simultaneously deliverd plan, with the aim to spare the salivary glands.

2011GezondheidArtikel

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