Background: Persons with profound intellectual and multiple disabilities (PIMD) are vulnerable when it comes to experiencing pain. Reliable assessment of pain-related behaviour in these persons is difficult. Aim To determine how pain items can be reliably scored in adults with PIMD. Methods: We developed …

Background: Adverse outcome pathway (AOP) networks are versatile tools in toxicology and risk assessment that capture and visualize mechanisms driving toxicity originating from various data sources. They share a common structure consisting of a set of molecular initiating events and key events, connected …

Background To gain insight into the role of plantar intrinsic foot muscles in fall-related gait parameters in older adults, it is fundamental to assess foot muscles separately. Ultrasonography is considered a promising instrument to quantify the strength capacity of individual muscles by assessing their …

Adverse Outcome Pathways (AOPs) are conceptual frameworks that tie an initial perturbation (molecular initiat- ing event) to a phenotypic toxicological manifestation (adverse outcome), through a series of steps (key events). They provide therefore a standardized way to map and organize toxicological …

Objective swallowing outcomes measure the physical swallowing function, while subjective outcomes measure swallowing perception. A test for swallowing capacity, measuring the ingestion of all consistencies is currently not available. Therefore, the Swallowing Proficiency for Eating And Drinking (SPEAD) …

This thesis is concerning effective use of fuel on board the ALP STRIKER. The recent transfer from heavy fuel oil, to the more expensive marine gas oil led to ongoing discussions about the effective use of fuel on board. The goal was to find the optimum propulsion configuration on board for any attainable …

fingerprints are a commonly exploited type of evidence and can be crucial in a criminal investigation. The process of individualization or exclusion of a donor relies on the comparison of ridge detail characteristics between a fingermark, found at a crime scene, and reference fingerprints, collected …

Formal elements are often used in art therapy assessment. The assumption is that formal elements are observable aspects of the art product that allow reliable and valid assessment of clients’ mental health. Most of the existing art therapy assessment instruments are based on clinical expertise. Therefore, …

Concerns about the negative consequences of the excessive underpricing of the current arrangement in the initial public offering (IPO) market for the provision of entrepreneurial finance—book building—have led to research into the viability of auctions for IPO pricing and allocation. IPO firms face a trade-off …

Het doel van deze studie is bepalen in hoeverre metingen van het handheld echografietoestel, de Philips VISIQ, verschillen met die van een conventioneel echografietoestel bij het meten van de diameter van de aorta abdominalis. Uit het onderzoek is gebleken dat de Philips VISIQ de abdominale aortadiameter, …