The goal of this research paper is to close the research gap between product focused strategy and customer focused strategy in SME`s. The cross-border region of North-Rhine Westphalia, Germany and Limburg, Netherlands is the target focus during the research. As the market is steadily evolving more …

Online working adds a new dimension to our jobs. When I see myself working and interacting, I’m involved very differently than when I only act from my own perspective. From my first-person and newly acquired second-person perspective, I have slowly but surely come to form an opinion about this. From …

Half of the medium-size cities of France are slowly disappearing. From social and economical weaknesses, they experience a rang of symptoms such as shrinkage, urban decay, ageing and impoverished populations that directly impact their spatial qualities and their very own identity. They need a spatial …

Our planet’s ecology and society are on a collision course, which manifests due to a contradiction in the assumptions of unlimited material growth fueling the linear economic paradigm. Our closed planetary ecosystem imposes confined amounts of space and a finite extent of resources upon its inhabitants. …

The global industrial economy is still predominantly linear, working according to the take-make-waste principle. This has affected the planet to a concerning amount, which is why the European Union signed the Paris Agreement, committing to a 1,5 to 2 degree scenario of global warming. In order to achieve …

Most endogenous viruses, an important proportion of eukaryote genomes, are doomed to slowly decay. Little is known, however, on how they evolve when they confer a benefit to their host. Bracoviruses are essential for the parasitism success of parasitoid wasps, whose genomes they integrated ~103 million …

Introduction: Neuromuscular diseases (NMD) are a heterogeneous group of acquired or inherited diseases affecting the peripheral nervous system and muscle mass. The consequences of NMD are loss of muscle mass, function, and posture. Loss of muscle mass causes weakness, a decrease in mobility and cardiac …

Traditional IMU based PDR systems suffer from rapidly growing drift effects due to the inherent bias of the inertial sensor. Many existing solutions to mitigate this problem use aiding sensors or information as heuristics or map data. We propose a new optimization framework to solve the PDR estimation problem …

According to myth, Rome was created more than 2,500 years ago on two hills. Romulus climbed the Palantine Hill and Remus took up position on a nearby hill, the Aventine Hill. From here, the city grew over seven hills into an unprecedented metropolis. Two millennia later, its inhabitants have barely …

Purpose – Over 8 per cent of the Dutch nursing home population is bedfast, and this number is slowly increasing. The quality of life (QoL) of this population is lower than that of residents who are still mobile. Little research has been conducted on how to improve the QoL of this bedfast population, …