Background Communicative participation is the most important outcome of speech and language therapy. However, there are no instruments to measure communicative participation in children. This paper focuses on assessing the psychometric properties of MyCommunication-Children, an item bank designed to …

Paratonia is a movement disorder characterized by involuntary muscle stiffening that affects nearly all individuals with advanced dementia, yet it remains poorly recognized in routine clinical practice. Often misinterpreted as intentional resistance to care, untreated paratonia may progress to muscle …

In recent years, care for people with severe mental illnesses (SMI) has shifted from institutional to recovery-based treatment in which informal caregivers often have an important role. However, their increased involvement has elevated issues such as role strain or burden of care, which indicates that …

BACKGROUND AND PURPOSE: Aphasia can profoundly affect an individual's identity. Yet studying identity in people with aphasia presents methodological challenges, as language, our primary medium for self-expression, is disrupted. This study explored how people with aphasia experience and reshape identity …

Background: Communicative participation is the most important outcome of speech and language therapy. Apatient-reported outcome measure (PROM) for children would help capture this outcome. Before this PROM can be developed, it is important to find out what situations children themselves find difficult …

Young adults with psychotic-spectrum disorder have lower odds of attaining educational goals, partly due to cognitive problems. Cognitive remediation (CR) could improve cognitive- and potentially academic functioning. The current study examined an adapted CR-intervention ‘Mindset’ aimed at academic functioning …

BACKGROUND: Communicative participation is the most important outcome of speech and language therapy, but there are no measurement instruments for children, adolescents, and young adults. This paper describes the development of MyCommunication-Youth: an item bank to measure self-reported communicative …

Hyperhomocysteinemia is a risk factor for cardiovascular disease, neurological disorders, and bone abnormalities. The key enzyme in homocysteine metabolism, cystathionine-β-synthase (CBS) is recognized as a target for new homocysteine-lowering therapies including enzyme replacement and gene therapy. …

Brain disorders, such as Alzheimer’s disease and epilepsy have been linked to an imbalance in excitatory and inhibitory (E/I) inputs in the brain. However, the molecular mechanisms underlying E/I balance and plasticity in the brain are largely unresolved. Inhibitory synapses have a strong impact on brain …

BACKGROUND: Communicative participation is the primary outcome of speech and language therapy for people with communication disorders. However, there are no instruments that measure communicative participation from the perspective of adolescents and young adults. Moreover, little research has been conducted …