Background: Despite improvement of tumour response rates in patients with progressive and metastatic cancer, immune checkpoint inhibitors (ICM) induce toxicities in cancer patients. Viscum album L. (VA, mistletoe) extracts are applied as add-on cancer therapy especially in German speaking countries and …

Rationale: Head and neck cancer (HNC) patients often have adverse changes in body composition. Loss of muscle mass and strength frequently occur, even when dietary intake is adequate. Nascent evidence suggests that a healthy lifestyle, including adequate physical activity (PA) and diet, may prevent muscle …

Background. There is an increasing need for a worldwide professional integration of conventional medicine and traditional/complementary whole medical systems (WMSs). However, the integration is perceived by conventional medicine as problematic or unacceptable, because of a supposed lack of evidence for …

Het vervoer van gevaarlijke stoffen over het spoor is een onderwerp dat steeds meer begint te spelen binnen de regio Twente. Het in 2015 vastgestelde risicoplafond wordt door verschillende oorzaken ruimschoots overschreden, waardoor de kans op een ongeval, hoewel nog steeds erg klein, toeneemt. Enerzijds …

Een ondernemende houding is onmisbaar voor werknemers van de toekomst. Daarom is er in het onderwijs veel aandacht voor het stimuleren van ondernemende vaardigheden. Self-efficacy overtuigingen vormen de basis van ondernemend gedrag. Om docenten te ondersteunen in het creëren van een ondernemende leeromgeving …

In dit onderzoek is de invloed van verschillende aspecten van de module Samenwerken op de self-efficacy bij samenwerken onderzocht. Een vso-havo-5-klas volgde gedurende tien weken een module samenwerken aan de hand van het Belbinteamrollenmodel, met als impliciet doel het vergroten van self-efficacy …

Very little is known about the personal goals of homeless people and how these relate to their quality of life (QoL). By using survey data on 407 homeless adults upon entry to the social relief system in 2011, we examined the personal goals of homeless adults and the association between their perceived …

The thesis project was devoted to a differentiation of different types of cancer cells checking the effectiveness of the novel anti-leukemia chemicals and exploring whether the best anti-leukemia targets also target bone cancers. The research question of this project is as follows: “How leukemia and …

Background: In addition to medical intervention and counseling, patients with cardiovascular disease (CVD) need to manage their disease and its consequences by themselves in daily life. Objective: The aim of this paper is to describe the development of "Vascular View," a comprehensive, multi-component, …

BACKGROUND: Seclusion is a controversial intervention. Efficacy with regard to aggressive behaviour has not been demonstrated, and seclusion is only justified for preventing safety hazards. Previous studies indicate that nursing staff factors may be predictors for seclusion, although methodological issues …