PURPOSE: To determine the impact of late radiation-induced toxicity on health-related quality of life (HRQoL) among patients with prostate cancer. PATIENTS AND METHODS: The study sample was composed of 227 patients, treated with external beam radiotherapy. Common Terminology Criteria for Adverse Events …

Small RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of equivalently …

Fragmentation of the environment affects the dispersal of Eurasian lynx (Lynx lynx). This also occurs in the Harz region, in central Germany, where in 2000 the Luchsprojekt Harz started reintroducing the Eurasian lynx. This constantly growing population causes lynx dispersal including high traffic volume …

As an essential basic principle of the European Union, the free movement of workers has been on everyone’s lips with the European Enlargement of Romania and Bulgaria in 2007. With the complete abolishment of the restrictions on the free movement of workers for Romanian and Bulgarian citizens in Germany …

Bioelectrical impedance analysis (BIA) may be used to assess fat free mass (FFM) with reasonable validity based on mean-level comparisons, but differences between BIA and DXA may vary by about 4 kg in an individual patient. These results require confirmation in a larger sample of HNC (Head and neck cancer) …

BACKGROUND: Although physical activity is beneficial for Parkinson's disease (PD) patients, many do not meet the recommended levels. The range of physical activity among sedentary PD patients is unknown, as are factors that determine this variability. Hence, we aimed to (1) assess daily physical activity …

BACKGROUND: Due to the rapidly increasing number of older people worldwide, the prevalence of frailty among older adults is expected to escalate in coming decades. It is crucial to recognize early onset symptoms to initiate specific preventive care. Therefore, early detection of frailty with appropriate …

Purpose To investigate the course of quality of life (QoL) among prostate cancer patients treated with external beam radiotherapy and to compare the results with QoL of a normal age-matched reference population. Conclusion Prostate cancer patients experience a small worsening of QoL as compared with …

The availability of real-life data sets is of crucial importance for algorithm and application development, as these often require insight into the specific properties of the data. Often, however, such data are not released because of their proprietary and confidential nature. We propose to solve this …

The Dutch version of the Brief Illness Perception Questionnaire is an appropriate instrument for measuring patients' perceptions in acute low back pain patients, showing acceptable internal consistency and reliability. Concurrent validity is adequate, however, the instrument may be unsuitable for detecting …