Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …

Purpose: A model is developed to analyse what personality traits impact entrepreneurial cognitive and social strategic decision-making skills, originating from the effectuation framework. Design/methodology/approach: 128 participants from an entrepreneurial pre-launch programme were assessed by experienced …

The aim of the present study was to predict the effect of inter-individual and inter-ethnic human kinetic variation on the sensitivity towards acute liver toxicity of lasiocarpine in the Chinese and the Caucasian population, and to derive chemical specific adjustment factors (CSAFs) by integrating variation …

It can be concluded that the HBM4EU serum sample preparation method is suitable for Effect-Directed Analysis. The method allows a recovery of all bioactive compounds of interest from serum in the EDA products, with little loss of compounds: bioassay spectra and chromatograms. Nevertheless, the HBM4EU …

Exhaust emissions from motorized vehicles are not only harmful to the environment but also on human health. At the same time, motorists are not necessarily aware of the adverse health effects resulting from their emissions. In this work, we use the health aspect as a primary motivation factor in the …

Exhaust emissions from motorized vehicles are not only harmful to the environment but also to human health. However, motorists are not necessarily aware of the adverse health effects resulting from their emissions. In this work, we use the health aspect as a primary motivation factor in the design of …

Highlights •Crime scene investigations are accompanied by cognitive challenges. •Introducing technologies at crime scenes requires research into the human factor. •Mobile technologies can impede the investigation without studying the impact.

Background Woman-centred care is a philosophy for midwifery care management of the childbearing woman. There is no mutually recognised internalised way in midwifery to provide woman-centred care. Objective To reveal midwives’ distinct perspectives about woman-centred care. Methods A Q-methodology …

Issues of race and discrimination towards the ethnic minorities have always existed in the United Kingdom. With the initiation of the EU referendum and Brexit, these issues have increased. Following the referendum, the media published news of hate crimes against Indian and Pakistani citizens. During …