Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

We give a refinement of the well known business model canvas by Osterwalder and Pigneur by splitting the basic blocks into further subblocks to reduce confusion and increase its expressive power. The splitting is used in an online tool which in addition comes with a set of questions to further structure …

The Foreign Account Tax Compliance Act (“FATCA”) is a very recent US tax regime with implications for international funds. FATCA’ complexities compounded with Treasury’s inconsistent approach towards FATCA resulted in unintended industry challenges. These inconsistencies and unintended challenges peaked …

Awareness regarding the challenges involved in creating a sustainable food system has affected the ways in which businesses market their products and how consumers decide whether to buy these products. Businesses directly communicate different quality aspects of their products to consumers mainly through …

Introduction: Elderly alcohol dependent patients can be discriminated based on the age of onset of alcohol use. This is relevant for their clinical problem presentation and for the course of treatment. Materials and methods: In this paper, problems of elderly patients are presented at intake in an addiction …

The number of displaced persons in the world has reached an exceedingly high amount. Due to conflicts and war in Syria, the number of displaced persons has increased. The European Union was not prepared for a refugee influx on this scale. Applications in The Netherlands are being delayed and the pressure …

Objective: Product Information Leaflets (PILs) are an important source of information for patients on their medication, but may cause confusion and questions. Patients then may seek clarification, for instance from pharmacy technicians. The aim of this study was to explore which questions pharmacy technicians …

The term “Internationalization at Home” and its definition were first introduced in 2001 (Crowther et al 2001). Since then, strongly related and overlapping concepts and definitions have emerged, notably Internationalization of the Curriculum and Campus Internationalization, which have led to confusion …

The importance of a near-native accent. This talk will discuss whether or not it is important for EFL-teachers to try and achieve a near-native generally accepted accent for their students. The focus will be on the credibility of non-native speakers of English while speaking English in a globalising …

Over the past few years the terms 'fair trade', 'sustainable' and 'organic' have become more present in combination with tea products in the supermarkets. These terms are used for many different goals. Some suppliers actually try to provide the consumer with a product that has been produced following …