Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

Aim: In-hospital prescribing errors (PEs) may result in patient harm, prolonged hospitalization and hospital (re)admission. These events are associated with pressure on healthcare services and significant healthcare costs. To develop targeted interventions to prevent or reduce in-hospital PEs, identification …

Voor veel jongeren in het hoger onderwijs (hbo en wo) is de studententijd een periode waarin regelmatig (veel) alcohol wordt gedronken. Daarnaast komt er in deze fase ook vaak voor het eerst drugsgebruik ter sprake (Trimbos-instituut, 2021). Dit middelengebruik brengt verscheidene risico’s met zich mee. …

Door middel van een praktijkgericht kwalitatief onderzoek is gekeken naar de feitelijke en gewenste situatie omtrent de toenemende lachgasproblematiek en delinquent gedrag binnen reclasseringstrajecten van GGZ Reclassering Fivoor. Om een zo compleet mogelijk beeld hierover te krijgen heeft er literatuur- …

Essential drug lists are used in several countries to ensure safe prescribing and to meet the needs of the national health care system. For medical education purposes, existing lists are in practice too extensive or outdated. There is as yet no broad-based consensus list of commonly prescribed drugs …

Cannabis is commonly characterized as the most normalized illicit drug. However, it remains a prohibited substance in most parts of the world, including Europe, and users can still be subject to stigmatization. The objective of this study is to assess to what extent and how cannabis users in different …

Drug consumption estimates are of relevance because of public health effects as well as associated criminal activities. Wastewater analysis of drug residues enables the estimation of drug consumption and drug markets. Short-term and long-term trends of cocaine, MDMA (ecstasy), amphetamine (speed) and …

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

The aim of this cross-sectional study is (1) to describe the socio-demographic characteristics of students with relatives with problematic substance use and to examine differences between students with and without relatives with problematic substance use in (2) health, (3) substance use and (4) study …