Post Covid Syndroom (PCS) is de term voor langdurig aanhoudende coronaklachten. Deze klachten bestaan hoofdzakelijk uit vermoeidheid, spierzwakte, mentale klachten en cognitieve problematiek. Omdat er nog veel onduidelijk is over PCS is het ook niet duidelijk hoe deze patiënten moeten worden behandeld, …

Background: Ventilation with lower positive end–expiratory pressure (PEEP) may cause loss of lung aeration in critically ill invasively ventilated patients. This study investigated whether a systematic lung ultrasound (LUS) scoring system can detect such changes in lung aeration in a study comparing …

The prevention and diagnosis of frailty syndrome (FS) in cardiac patients requires innovative systems to support medical personnel, patient adherence, and self-care behavior. To do so, modern medicine uses a supervised machine learning approach (ML) to study the psychosocial domains of frailty in cardiac …

SAMENVATTING Mensen met een ernstige psychiatrische aandoening (EPA) hebben een sterk verminderde levensver wachting in vergelijking met de algemene populatie, vooral veroorzaakt door fysieke aandoeningen. Een ongezonde leefstijl speelt een belangrijke rol in de verminderde levensverwachting bij mensen …

5% to 10% of all cancers are linked to gene mutations inherited from parents. The most common gene related to hereditary cancer is the p53 gene. It is a crucial tumor suppressor. However, the mutated gene is commonly inherited from one generation to another one. The functions of p53 resume to the activation …

People with a ‘severe mental illness’ (SMI) are those who suffer from a psychiatric illness for a prolonged period of time that seriously affects their social functioning, professional functioning and functioning in the community, and who are in need of professional care or treatment. SMI is not limited …

Background In adolescents with non-pathological and pathological joint hypermobility, gait deviations have been associated with pain and fatigue. It remains unclear what distinguishes the non-pathological form of joint hypermobility (JH) from pathological forms (i.e. hypermobile Ehlers-Danlos syndrome …

BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

Delirium is a neuropsychiatric syndrome characterized by disturbances of awareness, attention, cognitive functions, and behavior.1 It occurs in the severely ill, often older patients2 and is associated with prolonged hospitalization,3 institutionalization, increased costs, long-term cognitive decline, …

Objectives: Health problems in patients with heritable connective tissue disorders (HCTD) are diverse and complex and might lead to lower physical activity (PA) and physical fitness (PF). This study aimed to investigate the PA and PF of children with heritable connective tissue disorders (HCTD). Methods: …