HBO Kennisbank

22 Resultaten

Sorteer op:

Zocht je misschien: vijf, vier?

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells

Roelofs, Anke J.; Hulley, Philippa A.; van der Heij-Meijer, Annemieke; Ebetino, Frank H.; Russell, R. Graham G.; Shipman, Claire M.

Bisphosphonates (BPs) are widely used in the treatment of osteolytic bone disease associated with multiple myeloma, and have been demonstrated to exert antitumor effects both in vitro and in vivo. However, the precise molecular mechanisms involved in the direct antitumor effects of BPs in vitro are not …

2006-04-17AlgemeenArtikel

Production of plasminogen activators and inhibitor by serially propagated endothelial cells from adult human blood vessels

van Hinsbergh, V W; Binnema, D; Scheffer, M A; Sprengers, E D; Kooistra, T; Rijken, D C

Endothelial cells were isolated from arteries and veins obtained from elderly people at autopsy and propagated for 37 to 69 population doublings. The cells secreted tissue-type plasminogen activator (t-PA) and PA inhibitor-1, and, after subculturing, urokinase-type PA (u-PA) antigen. The following differences …

1987-07-01AlgemeenArtikel

1 2 3

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells

Production of plasminogen activators and inhibitor by serially propagated endothelial cells from adult human blood vessels

Over HBO Kennisbank