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Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis - a pilot randomized controlled trial

Franziska Weber (Onderzoeker); Corelien Kloek (Onderzoeker); Sandra Stuhrmann (Onderzoeker); Yannick Blum (Onderzoeker); Christian Grüneberg (Onderzoeker); Cindy Veenhof (Lector)

Background: Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage people in physical activity and disease management. Therefore, we conducted a pilot …

2024GezondheidArtikel

Microneedling in Abdominal Scarring after DIEP-flap Breast Reconstruction to Improve Scar Quality

Kristel Everaars (Onderzoeker); Audrey Meulendijks (Onderzoeker); Esther Tjin (Onderzoeker); Anne Eskes (Onderzoeker); Stefan Hummelink (Onderzoeker); Erik de Laat (Onderzoeker); Dietmar Ulrich (Onderzoeker)

Background: Deep inferior epigastric perforator (DIEP) flap breast reconstruction leads to large scars in the breast and abdominal region. Common symptoms related to abdominal scarring include changes in color, stiffness, thickness, and irregularity of the skin. The aim of this study was to examine whether …

2024GezondheidArtikel

Development and internal validation of a multivariable prognostic model to predict chronic pain after a new episode of non-specific idiopathic, non-traumatic neck pain in physiotherapy primary care practice

Martine Verwoerd (Onderzoeker); Harriët Wittink (Lector); François Maissan (Onderzoeker); Marc Teunis (Onderzoeker); Sander M.J. van Kuijk (Onderzoeker); Rob Smeets (Onderzoeker)

Objective To develop and internally validate a prognostic model to predict chronic pain after a new episode of acute or subacute non-specific idiopathic, non-traumatic neck pain in patients presenting to physiotherapy primary care, emphasising modifiable biomedical, psychological and social factors. Design …

2024GezondheidArtikel

The efficacy of a blended intervention to improve physical activity and protein intake for optimal physical recovery after oncological gastrointestinal and lung cancer surgery, the Optimal Physical Recovery After Hospitalization (OPRAH) trial

de Leeuwerk, Marijke; de Groot, Vincent; Dam, Suzanne ten; Kruizenga, Hinke; Weijs, Peter (Lectoraat Voeding En Beweging); Geleijn, Edwin; van der Leeden, Marike; van der Schaaf, Marike (Lectoraat Revalidatie Bij Complexe Zorg); Dickhoff, Chris; Besselink, Marc G.; Tuynman, Jurriaan B.; van Berge Henegouwen, Mark I.; Erdmann, Joris I.; Huijsmans, Rosalie J.; van der Ploeg, Hidde P.; Eskes, Anne M. (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); Pijnappels, Mirjam A.G.M.; van Leeuwen, Liesbeth Schuijs; Smits, Anke B.; van Dijk, Jasmijn; Grimbergen, Eva

Background: Improving physical activity, especially in combination with optimizing protein intake, after surgery has a potential positive effect on recovery of physical functioning in patients after gastrointestinal and lung cancer surgery. The aim of this randomized controlled trial is to evaluate the …

2023-11-27AlgemeenArtikel

A multidisciplinary lifestyle program for metabolic syndrome-associated osteoarthritis

Walrabenstein, Wendy; Wagenaar, Carlijn A.; van de Put, Marieke; van der Leeden, Marike; Gerritsen, Martijn; Twisk, Jos W.R.; van der Esch, Martin (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); van Middendorp, Henriët; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Roorda, Leo D.; van Schaardenburg, Dirkjan

Objective To determine the effectiveness of the “Plants for Joints” multidisciplinary lifestyle program in patients with metabolic syndrome-associated osteoarthritis (MSOA). Design Patients with hip or knee MSOA were randomized to the intervention or control group. The intervention group followed a 16-week …

2023-11AlgemeenArtikel

L2026M+G2032R variant confers resistance to ROS1 tyrosine kinase inhibitors in SCL34A2-ROS1 overexpressing Ba/F3 cells through a reduced ATP binding pocket volume

Dijkhuizen, Christa (Biomolecules & Health); Korthuis, Patrick; Vilachã, Juliana F.; Smelt, Maaike; van der Wekken, Anthonie; van den Berg, Anke; Drayer, Lyndsay

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

2023-10-21GezondheidConferentiebijdrage

Increasing trends in a low 5-min Apgar score among (near) term singletons: a Dutch nationwide cohort study

C.E. Tacke; W. Onland; P.C.A.M. Bakker; F. Groenendaal; A.N. Rosman; L. Broeders; J.V. Been; A.C.J. Ravelli

Objective To investigate trends in low Apgar scores in (near) term singletons using the Dutch Perinatal Registry. Methods In a cohort of 1,583,188 singletons liveborn ≥35 weeks of gestation in the period 2010–2019, we studied trends in low 5-min Apgar scores (<7 and <4) using Cochrane Armitage trend …

2023-10-18GezondheidArtikel

Fatigue in children and adolescents after burns

Cramer-Kruit, Jessica J J; Akkerman, Moniek; Mouton, Leonora J; Spek, Bea; Scholten-Jaegers, Sonja M H J; van der Woude, Lucas H V; Nieuwenhuis, Marianne K (Healthy Ageing, Allied Health Care And Nursing); Niemeijer, Anuschka

PURPOSE: Describe prevalence and severity of fatigue in children and adolescents with burns during six months after hospital discharge, identify potential explanatory variables, and examine the relationship with exercise capacity. MATERIALS AND METHODS: Fatigue was assessed using the Pediatric-Quality-of-Life-Inventory-Multidimensional-Fatigue-Scale …

2023-09-18AlgemeenArtikel

Nutritional and exercise interventions in individuals with sarcopenic obesity around retirement age: a systematic review and meta-analysis

Eglseer, Doris; Traxler, Mariella; Schoufour, Josje D (Lectoraat Voeding En Beweging); Weijs, Peter J M (Lectoraat Voeding En Beweging); Voortman, Trudy; Boirie, Yves; Cruz-Jentoft, Alfonso J; Reiter, Lea; Bauer, Silvia

Context Retirement is an opportune time for people to establish new healthy routines. Exercise and nutritional interventions are promising in the prevention and treatment of sarcopenic obesity. Objective This systematic review aimed to assess the effectiveness of nutritional and exercise interventions …

2023-09AlgemeenArtikel

A multidisciplinary lifestyle program for rheumatoid arthritis: the 'Plants for Joints' randomized controlled trial

Walrabenstein, Wendy; Wagenaar, Carlijn A; van der Leeden, Marike; Turkstra, Franktien; Twisk, Jos W R; Boers, Maarten; van Middendorp, Henriët; Weijs, Peter J M (Lectoraat Voeding En Beweging); van Schaardenburg, Dirkjan

Objective To determine the effect of a multidisciplinary lifestyle program in patients with RA with low–moderate disease activity. Methods In the ‘Plants for Joints’ (PFJ) parallel-arm, assessor-blind randomized controlled trial, patients with RA and 28-joint DAS (DAS28) ≥2.6 and ≤5.1 were randomized …

2023-08AlgemeenArtikel

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