Heme is a suggested limiting factor in peroxidase production by Aspergillus spp., which are well-known suitable hosts for heterologous protein production. In this study, the role of genes coding for coproporphyrinogen III oxidase (hemF) and ferrochelatase (hemH) was analyzed by means of deletion and …

Background: Patients with Senning repair for complete transposition of the great arteries (d-TGA) show an impaired exercise tolerance. Our aim was to investigate changes in exercise capacity in children, adolescents and adults with Senning operation. Methods: Peak oxygen uptake (peak VO2), oxygen pulse …

Objectives Patients who underwent corrective surgery for tetralogy of Fallot (TOF) have increased long-term risk of cardiovascular morbidity and mortality. Yet, limited information is available on how to evaluate the risk in this population. Therefore, the aim of this study was to investigate the prognostic …

Tijdens het plenaire debat over het wetsvoorstel Wijziging van de WEB, WSF 2000, WTOS en LCW in verband met de regeling in de WEB van een minimumomvang van het in instellingstijd verzorgde onderwijsprogramma (TK 2006-2007, nr. 31048), is door staatssecretaris van Bijsterveldt een beleidsevaluatie van …