BACKGROUND: Physical activity may be both a risk and protective factor for falls and fall-related fractures. Despite its positive effects on muscle and bone health, physical activity also increases exposure to situations where falls and fractures occur. This paradox could possibly be explained by frailty …

Background: Little is known, whether physical workload and musculoskeletal complaints (MSCs) have an impact on the intended or actual dropout of nursing students in the later years of their degree program. Purpose: Studying the determinants of intention to leave and actual dropout from nursing education. …

Rationale: Patients with cancer of the upper gastrointestinal tract or lung are more likely to present with malnutrition at diagnosis than, for instance, patients with melanoma. Low muscle mass is an indicator of malnutrition and can be determined by computed tomography (CT) analysis of the skeletal …

INTRODUCTION: Patients with COVID-19-related acute respiratory distress syndrome (ARDS) have been postulated to present with distinct respiratory subphenotypes. However, most phenotyping schema have been limited by sample size, disregard for temporal dynamics, and insufficient validation. We aimed to …

Baron and Kenny's (1986) causal steps approach has been widely used by researchers in mediation analyses. Yet, recently, some researchers have begun to argue that Baron and Kenny's approach is not an appropriate method for mediation analysis, and that contemporary or new methods that are based on bootstrapping …

Aims:  To evaluate the effects of the implementation of a professional practice model based on Magnet principles on the nurse work environment in a Dutch teaching hospital.  Design:  A quasi-experimental study.  Methods:  Data were collected from registered nurses working on the clinical wards and outpatient …

BACKGROUND : There is uncertainty about how much positive end-expiratory pressure (PEEP) should be used in patients with acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19). OBJECTIVE : To investigate whether a higher PEEP strategy is superior to a lower PEEP strategy …

BACKGROUND: Prognostic assessments of the mortality of critically ill patients are frequently performed in daily clinical practice and provide prognostic guidance in treatment decisions. In contrast to several sophisticated tools, prognostic estimations made by healthcare providers are always available …

Societal transitions require activities of multiple stakeholders on different systemic levels. Designers and design researchers are often involved in supporting specific interventions and sometimes in enabling and facilitating entire processes. Practices and literature in ‘co-creation ecosystems’ are …

Panorama Films is an Italian-based production and service company, for feature films, commercials, photographic shoots and more; and assists foreign production companies in all aspects of the production, such as budget allocation, crew, locations, etc. Panorama Films plans to implement a radical change …