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Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer

Anja Thronicke (Onderzoeker); Megan L. Steele (Onderzoeker); Christian Grah (Onderzoeker); Burkhard Matthes (Onderzoeker); Friedemann Schad (Onderzoeker)

Background: Despite improvement of tumour response rates in patients with progressive and metastatic cancer, immune checkpoint inhibitors (ICM) induce toxicities in cancer patients. Viscum album L. (VA, mistletoe) extracts are applied as add-on cancer therapy especially in German speaking countries and …

2017-12-13GezondheidArtikel

Series: Practical guidance to qualitative research

Irene Korstjens; Albine Moser

In the course of our supervisory work over the years we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called frequently asked questions (FAQs). This series of four articles intends to provide novice researchers with practical guidance for conducting high-quality …

2017-12-05GezondheidArtikel

Series: Practical guidance to qualitative research

Albine Moser; Irene Korstjens

In the course of our supervisory work over the years, we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called frequently asked questions (FAQs). This series of four articles intends to provide novice researchers with practical guidance for conducting high-quality …

2017-12-04GezondheidArtikel

Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (STEER OA):

2017-12AlgemeenArtikel

Lifestyle approaches for people with intellectual disabilities

Steenbergen, Rianne (Healthy Ageing, Allied Health Care And Nursing); van der Schans, Cees P.; van Wijck, Ruud; de Jong, Johan (Healthy Lifestyle, Sports And Physical Activity); Waninge, Aly (Participation And Health Of Persons With Intellectual And Visual Disabilities)

BACKGROUND: Health care organizations supporting individuals with intellectual disabilities (IDs) carry out a range of interventions to support and improve a healthy lifestyle. However, it is difficult to implement an active and healthy lifestyle into daily support. The presence of numerous intervention …

2017-11-01Recreatie, Beweging & Sport; …Andersoortig materiaal

Validation and refinement of prediction models to estimate exercise capacity in cancer survivors using the steep ramp test

Stuiver, Martijn M (Faculteit Gezondheid); Kampshoff, Caroline S; Persoon, Saskia; Groen, Wim; van Mechelen, Willem; Chinapaw, Mai J M; Brug, Johannes; Nollet, Frans; Kersten, Marie-José; Schep, Goof; Buffart, Laurien M

OBJECTIVE: To further test the validity and clinical usefulness of the steep ramp test (SRT) in estimating exercise tolerance in cancer survivors by external validation and extension of previously published prediction models for peak oxygen consumption (Vo2peak) and peak power output (Wpeak). DESIGN: …

2017-11AlgemeenArtikel

Risk factors for lower-extremity injuries among contemporary dance students

van Seters, Christine; van Rijn, Rogier M; van Middelkoop, Marienke; Stubbe, Janine H

OBJECTIVE: To determine whether student characteristics, lower-extremity kinematics, and strength are risk factors for sustaining lower-extremity injuries in preprofessional contemporary dancers. DESIGN: Prospective cohort study. SETTING: Codarts University of the Arts. PATIENTS: Forty-five first-year …

2017-10-10AlgemeenArtikel

Diagnostic accuracy of clinical decision rules to exclude fractures in acute ankle injuries

Barelds, Ingrid; Krijnen, Wim P (Statistical Techniques For Applied Research); van de Leur, Johannes P; van der Schans, Cees P; Goddard, Robert

BACKGROUND: Ankle decision rules are developed to expedite patient care and reduce the number of radiographs of the ankle and foot. Currently, only three systematic reviews have been conducted on the accuracy of the Ottawa Ankle and Foot Rules (OAFR) in adults and children. However, no systematic review …

2017-09-01Gezondheid; …Andersoortig materiaal

The intensive care medicine research agenda in nutrition and metabolism

Arabi, Yaseen M; Casaer, Michael P.; Chapman, Marianne; Heyland, Daren K.; Ichai, Carole; Marik, Paul E.; Martindale, Robert G.; McClave, Stephen A.; Preiser, Jean-Charles; Reignier, Jean; Rice, Todd W.; Van den Berghe, Greet; van Zanten, Arthur R. H.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging)

PURPOSE: The objectives of this review are to summarize the current practices and major recent advances in critical care nutrition and metabolism, review common beliefs that have been contradicted by recent trials, highlight key remaining areas of uncertainty, and suggest recommendations for the top …

2017-09AlgemeenAndersoortig materiaal

Opportunities of mHealth in preconception care: preferences and experiences of patients and health care providers and other involved professionals

M.R. van Dijk; M.P.H. Koster; A.N. Rosman; R.P.M. Steegers-Theunissen

Background: The importance of the preconception period and preconception care (PCC) are broadly acknowledged and the potential benefits regarding health promotion have been studied extensively. PCC provides the opportunity to identify, prevent, and treat modifiable and nonmodifiable risk factors to optimize …

2017-08-17GezondheidArtikel

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