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Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands

Julia L.M. Bels; Steven Thiessen; Rob J.J. van Gassel; A. Beishuizen; Ashley de Bie Dekker; Vincent Fraipont; Stoffel Lamote; Didier Ledoux; Clarissa Scheeren; Elisabeth de Waele; Arthur R.H. van Zanten; Laura Bormans-Russell; Bas C.T. van Bussel; Marlies M.J. Dictus; Tom Fivez; Ingeborg Harks; Iwan C.C. van der Horst; Joop Jonckheer; Hugues Marechal; Paul B. Massion; Ingrid Meex; Michelle C. Paulus; Martin Rinket; Susanne van Santen; Katrien Tartaglia; Adam M. Deane; Frieda Demuydt; Zudin Puthucheary; Lilian Vloet; P.J.M. Weijs; Sander M.J. van Kuijk; Marcel C.G. van de Poll; Dieter Mesotten

Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes in critically …

2024-08-17GezondheidArtikel

Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe)

Bels, Julia L M; Thiessen, Steven; van Gassel, Rob J J; Beishuizen, Albertus; De Bie Dekker, Ashley; Fraipont, Vincent; Lamote, Stoffel; Ledoux, Didier; Scheeren, Clarissa; De Waele, Elisabeth; van Zanten, Arthur R H; Bormans-Russell, Laura; van Bussel, Bas C T; Dictus, Marlies M J; Fivez, Tom; Harks, Ingeborg; van der Horst, Iwan C C; Jonckheer, Joop; Marechal, Hugues; Massion, Paul B; Meex, Ingrid; Paulus, Michelle C; Rinket, Martin; van Santen, Susanne; Tartaglia, Katrien; Deane, Adam M; Demuydt, Frieda; Puthucheary, Zudin; Vloet, Lilian C M; Weijs, Peter J M (Lectoraat Voeding En Beweging); van Kuijk, Sander M J; van de Poll, Marcel C G; Mesotten, Dieter

Background Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes …

2024-08-17AlgemeenArtikel

European educational practices for the critical care nursing profession - Let's align for the future

San Jose, Alicia; Blanchard, Pierre-Yves; van Mol, Margo; Rood, Paul J.T.; Stilma, Willemke (Urban Vitality)

2024-08AlgemeenArtikel

A Prospective, Longitudinal Study Evaluating the Efficacy of an Automated Secretion Removal Technology

Sinnige, Jante S; Karbing, Dan S; Valk, Christel M A; Schultz, Marcus J; Rees, Stephen E; Paulus, Frederique (Lectoraat Critical Care)

BACKGROUND: Endotracheal suctioning causes discomfort, is associated with adverse effects, and is resource-demanding. An artificial secretion removal method, known as an automated cough, has been developed, which applies rapid, automated deflation, and inflation of the endotracheal tube cuff during the …

2024-08AlgemeenArtikel

Epidemiology, ventilation management and outcomes of COVID–19 ARDS patients versus patients with ARDS due to pneumonia in the Pre–COVID era

Background: Ventilation management may differ between COVID–19 ARDS (COVID–ARDS) patients and patients with pre–COVID ARDS (CLASSIC–ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC–ARDS also exist in COVID–ARDS. Methods: Individual patient data analysis …

2024-08AlgemeenArtikel

Effect of automated versus conventional ventilation on mechanical power of ventilation-A randomized crossover clinical trial

Buiteman-Kruizinga, Laura A.; Neto, Ary Serpa; Botta, Michela; List, Stephanie S.; de Boer, Ben H.; van Velzen, Patricia; Bühler, Philipp Karl; Wendel Garcia, Pedro D.; Schultz, Marcus J.; van der Heiden, Pim L. J.; Paulus, Frederique (Lectoraat Critical Care)

Introduction Mechanical power of ventilation, a summary parameter reflecting the energy transferred from the ventilator to the respiratory system, has associations with outcomes. INTELLiVENT–Adaptive Support Ventilation is an automated ventilation mode that changes ventilator settings according to algorithms …

2024-07AlgemeenArtikel

Effects of closed loop ventilation on ventilator settings, patient outcomes and ICU staff workloads - A systematic review

Goossen, Robin L.; Schultz, Marcus J.; Tschernko, Edda; Chew, Michelle S.; Robba, Chiara; Paulus, Frederique (Lectoraat Critical Care); Van Der Heiden, Pim L.J.; Buiteman-Kruizinga, Laura A.

BACKGROUNDLung protective ventilation is considered standard of care in the intensive care unit. However, modifying the ventilator settings can be challenging and is time consuming. Closed loop modes of ventilation are increasingly attractive for use in critically ill patients. With closed loop ventilation, …

2024-06-01AlgemeenArtikel

Person-Centred Pain Measurement in the ICU: A Multicentre Clinimetric Comparison Study of Pain Behaviour Observation Scales in Critically Ill Adult Patients with Burns

de Jong, Alette E.E.; Tuinebreijer, Wim E.; Hofland, Helma W.C.; Van Loey, Nancy E.E. (Lectoraat Geïntegreerde Complexe Zorg)

Pain in critically ill adults with burns should be assessed using structured pain behavioural observation measures. This study tested the clinimetric qualities and usability of the behaviour pain scale (BPS) and the critical-care pain observation tool (CPOT) in this population. This prospective observational …

2024-06AlgemeenArtikel

The authors reply

Boukje Dijkstra; Lisette Schoonhoven; Johannes G. van der Hoeven; Lilian Vloet (Lector)

Online letter to the editor Rihimi-Bashar et al (1)

2024-06GezondheidArtikel

Opinions and priorities for an e-health platform: A member consultation from an intensive care patient organisation

Anna Zacharelou; Mel Major; Puck van der Meer; Marike van der Schaaf; Lilian Vloet; Margo M.C. van Mol

Background: To prevent deterioration after admission to the intensive care unit (ICU), and to improve rehabilitation, the ICU team should use digital technologies to provide comprehensive and practical information alongside personalised support for survivors and their family members. However, a knowledge …

2024-05-09GezondheidArtikel

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