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Effects of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity

Naaktgeboren, Willeke R.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker); Van Harten, Wim H.; Aaronson, Neil K.; Scott, Jessica M.; Sonke, Gabe; Van Der Wall, Elsken; Velthuis, Miranda; Leiner, Tim; Teske, Arco J.; May, Anne M.; Groen, Wim G.

Objective Animal data suggest that exercise during chemotherapy is cardioprotective, but clinical evidence to support this is limited. This study evaluated the effect of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity. Methods This is a follow-up study of two previously …

2023-10-30AlgemeenArtikel

Fatigue in children and adolescents after burns

Cramer-Kruit, Jessica J J; Akkerman, Moniek; Mouton, Leonora J; Spek, Bea; Scholten-Jaegers, Sonja M H J; van der Woude, Lucas H V; Nieuwenhuis, Marianne K (Healthy Ageing, Allied Health Care And Nursing); Niemeijer, Anuschka

PURPOSE: Describe prevalence and severity of fatigue in children and adolescents with burns during six months after hospital discharge, identify potential explanatory variables, and examine the relationship with exercise capacity. MATERIALS AND METHODS: Fatigue was assessed using the Pediatric-Quality-of-Life-Inventory-Multidimensional-Fatigue-Scale …

2023-09-18AlgemeenArtikel

The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors

Erik M. Donker; Hayaudin Osmani; David J. Brinkman; Floor van Rosse; Ben Janssen; Wilma Knol; Glenn Dumont; Jelle Tichelaar (Lector)

Abstract Purpose The primary aim of this study was to investigate the effect of including the Dutch National Pharmacotherapy Assess ment (DNPA) in the medical curriculum on the level and development of prescribing knowledge and skills of junior doctors. The secondary aim was to evaluate the relationship …

2023-07-31GezondheidArtikel

Cohort profile

van den Boom, Wijnand; van Dijk, Mart; Snijders, Bianca; Luijben, Guus; van der Laan, Jan; Euser, Saskia; Sanders, Jet G.; Buitenhuis, Anne H.; Spruijt, Pita; Kroese, Floor; Lambooij, Mattijs; Muhren, Yvette; Tak, Nannah; van der Swaluw, Koen; van Rossum, Caroline; Nielen, Thijs; Elberse, Janneke; Renes, Reint Jan (Lectoraat Psychologie Voor Een Duurzame Stad); Leurs, Mariken; de Bruin, Marijn

This ‘cohort profile’ aims to provide a description of the study design, methodology, and baseline characteristics of the participants in the Corona Behavioral Unit cohort. This cohort was established in response to the COVID-19 pandemic by the Dutch National Institute for Public Health and the Environment …

2023-07-31AlgemeenArtikel

Effects of major urban redesign on sedentary behavior, physical activity, active transport and health-related quality of life in adults

Nicole Stappers; Marleen Bekker; Maria Jansen; Stef Kremers; Nanne de Vries; Jasper Schipperijn; Dave Van Kann

Background: The built environment is increasingly recognized as a determinant for health and health behaviors. Existing evidence regarding the relationship between environment and health (behaviors) is varying in significance and magnitude, and more high-quality longitudinal studies are needed. The aim …

2023-06-15Recreatie, Beweging & SportArtikel

Short-term and long-term increased mortality in elderly patients with burn injury

FRAIL group; Dutch Burn Repository group

BACKGROUND: The population of elderly patients with burn injuries is growing. Insight into long-term mortality rates of elderly after burn injury and predictors affecting outcome is limited. This study aimed to provide this information. METHODS: A multicentre observational retrospective cohort study …

2023-01-17Gezondheid; …Artikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

The effects of the COVID‑19 lockdowns on motor skill development of 6‑ and 7‑year old children in the Netherlands: a longitudinal study

den Uil, Anne R. (Urban Vitality); van Doorn, Hemke (Urban Vitality); Schweitzer, Mandy (Urban Vitality); Janssen, Mirka (Lectoraat Bewegen In En Om School); Scholte, Ron H. J.; Busch, Vincent

Background The closing of schools and sports clubs during the COVID-19 lockdown raised questions about the possible impact on children’s motor skill development. Therefore, we compared motor skill development over a one-year period among four different cohorts of primary school children of which two …

2023AlgemeenArtikel

Work ability among employees 2–10 years beyond breast cancer diagnosis: Late treatment effects and job resources - A longitudinal study

Boelhouwer, Ingrid G. (Faculteit Maatschappij En Recht (Fmr)); Vermeer, Willemijn (Lectoraat Psychologie Voor Een Duurzame Stad); van Vuuren, Tinka

BACKGROUND: The number of workers who have previously undergone a cancer treatment is increasing, and possible late treatment effects (fatigue, physical and cognitive complaints) may affect work ability. OBJECTIVE: The aim of the study was to investigate the impact of late treatment effects and of job …

2023AlgemeenArtikel

Course of recovery of respiratory muscle strength and its associations with exercise capacity and handgrip strength: A prospective cohort study among survivors of critical illness

Major, Mel (Urban Vitality); van Egmond, Maarten (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Dettling-Ihnenfeldt, Daniela; Ramaekers, Stephan (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Engelbert, Raoul (Urban Vitality); van der Schaaf, Marike (Lectoraat Revalidatie Bij Complexe Zorg)

Background Mechanical ventilation affects the respiratory muscles, but little is known about long-term recovery of respiratory muscle weakness (RMW) and potential associations with physical functioning in survivors of critical illness. The aim of this study was to investigate the course of recovery of …

2023AlgemeenArtikel

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