To date, a range of qualitative and mixed-methods approaches have been applied to assess the age-friendliness of cities and communities. The Age-Friendly Cities and Communities Questionnaire (AFCCQ) has been developed to fill a gap for a systematic quantitative method approach to evaluate baseline age-friendliness …

Abstract Objectives Only studying effectiveness of lifestyle interventions for people with severe mental illness (SMI) is insufficient for policy making. As budgets for healthcare are limited, policy makers face the problem of allocating scarce healthcare resources. Cost-effectiveness studies are needed, …

In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change …

Some individuals, even when heavily exposed to an infectious tuberculosis patient, do not develop a specific T-cell response as measured by interferon-gamma release assay (IGRA). This could be explained by an IFN-γ-independent adaptive immune response, or an effective innate host response clearing Mycobacterium …

Introduction While principles of neuroplasticity and motor learning emphasise the potential of high dosage of physical rehabilitation in children and adolescents with acquired brain injury (ABI) during the subacute phase, we lack empirical evidence to demonstrate its impact in terms of meaningful outcomes. …

This thesis investigated how homeostatic resilience can be determined based on the response of various biomarkers during and after a standardised bicycle ergometer test. The test model had to be reproducible and widely applicable to people with varying health statuses. To this end, two controlled human …

Background: to optimize prehabilitation for patients with oesophageal cancer, insight is required into the response to prehabilitation, and factors affecting this response. This study investigated (1) the response to prehabilitation in patients with oesophageal cancer following neoadjuvant treatment, …

Introduction: This study evaluates the course of physical fitness and nutritional status during curative therapy for esophageal cancer, after implementation of a prehabilitation program. Additionally, the impact of baseline physical fitness level and severe postoperative complications on the course of …

Fluorescent Penetrant Inspection (FPI) is a widely used inspection technique in the aerospace industry. Because of the aging aerospace sector, and because of the safety-criticality of the inspection, aerospace companies aim to automate (parts of this) inspection process to support inspectors. This paper …

Objectives This paper is the first multidisciplinary study into the impact of new skill requirements in the job on absenteeism. The aim of this study was to investigate whether economic skills obsolescence (ESO) increased both absence frequency and average duration mediated by burnout and/or work engagement. …