Obesity is a growing global burden with numerous significant health implications, including a higher risk of developing Alzheimer’s disease (AD). This study investigates the role of obese adipose tissue on AD pathology in male APPswe/PSEN1-dE9 (APP/PSEN-1) transgenic mice, with a focus on cognitive decline, …

Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

Overweight and obesity are some of the biggest food-related problems in the world and affect more than 2 billion people worldwide. One of the factors of this problem is the change in the Dutch food environment. Food is getting more processed, and the amount of fat and sugary food is growing while their …

Background & aims: Overweight and obesity can cause several health risks, and weight loss can help reduce them. However, weight loss in older adults is associated with loss of muscle mass and bone mineral density. To prevent this, it is important to monitor changes in FFM. Bioelectrical impedance analysis …

Introduction A rapidly increasing patient group is older adults with obesity and type 2 diabetes. The risk of accelerated muscle loss is prominent in this patient group. This population could benefit from weight loss, at the cost of increased risk of muscle loss and sarcopenia. Previous studies showed …

This study, titled Sweetening the Deal, considers policy interventions to reduce sugar consumption. The study addresses the research question: To what extent does public opinion in the Netherlands and in the United Kingdom either correspond or contrast to policy approaches being taken by their governments …

The prevalence of obesity has almost tripled in the last four decades and is therefore an increasing threat to human health. Overnutrition – the excessive consumption of energy or nutrients, exceeding energy requirements – is believed to be one of the root causes of overweight and obesity. In literature, …

From the thesis: "Summary Metabolic diseases that are characterized by a disturbance in energy balance because of feeding behavior, such as obesity and anorexia are known to be a world-wide problem. A better understanding in central regulation of energy intake and metabolism could give more insight in …

This export marketing plan will identify the British E-bike market for Mihatra BV, a medium sized Dutch producer of E-bikes. The objective of the plan is to find out what the best market positioning and marketing would be for Mihatra in the United Kingdom. The central research question is therefore: …

In this study the following question will be examineted: How does the existing treatment for the eating disorder obesity within PsyQ, affect the negative body image of this patients? Body dysmorphic means what people think and feel about there bodies and what tis means for their daily doing. A negative …