The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use …

In deze casestudy leest u hoe de dubbele diagnose (dd) cliënt te werk gaat in zijn of haar behandeling. Ik richt mij op de klinisch dynamische behandelgroep. De dd cliënten uit deze groep hebben voornamelijk een hoofddiagnose op de as II (persoonlijkheidsstoornissen) in combinatie met een middelen-afhankelijkheids-problematiek. …

There are two aims of this thesis; one is selecting 2n pollen producers from F1 hybrids of T. gesneriana x T. fosteriana tulip hybrids crossing experiment. Furthermore, to test one year old tulip seedlings for ploidy levels of the F1 progenies in order to determine the result of the function of the 2n …

Genomics has multiplied the number of targets for new therapeutic interventions, but this has not yet lead to a marked increase of pharma pipeline outputs. The complexity of protein function in higher order biological systems is often underestimated. Translation from in vitro and in vivo results to the …

Bisphosphonates (BPs) are widely used in the treatment of osteolytic bone disease associated with multiple myeloma, and have been demonstrated to exert antitumor effects both in vitro and in vivo. However, the precise molecular mechanisms involved in the direct antitumor effects of BPs in vitro are not …