Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

In Sicht von oben, ‘Powers of Ten’ und Bildpolitiken der Vertikalität (Spector Books, Leipzig, 2022) German media theorist and curator Vera Tollmann analyses the power aspects of the technical view from above. The context here is not so much the first manned flight with a balloon in 1783 in Paris but …

De Nederlandse bevolking groeit samen met de stedelijke regio’s. Voor veel mensen in deze stedelijke regio’s zijn de publieke groenstructuren hun dagelijks contact met de natuur. Uit onderzoek blijkt dat de zulk contact met de natuur positief meetbare fysieke en psychologische effecten heeft. Hoewel …

Het verschil in denkwijze voor het toepassen van weidegang op het melkveebedrijf van veehouder en student. Het laat zien wat de huidige trendlijn is en wat de verwachtte trendlijn gaat voor de komende generatie omtrent weidengang toepassen op het melkveebedrijf.

The synthesis of aromatic compounds from biomass-derived furans is a key strategy in the pursuit of a sustainable economy. Within this field, a Diels–Alder/aromatization cascade reaction with chitin-based furans is emerging as a powerful tool for the synthesis of nitrogen-containing aromatics. In this …

Background For families with adolescent children, the transition to adulthood is usually challenging. This period may be extra demanding for families with a child with profound intellectual and multiple disabilities due to the child's strong and persistent support needs. To support these families during …

The student works within a team of 5 that comprises at least 3 different professions (at the Hanze: physiotherapist, dietetics, speech therapists, occupational therapy, and nursing). Based on the metamodel of interprofessional development (Jan Jaap Reinders, 2022) the student prepares the R-ISDs by home …

Electric vehicles have penetrated the Dutch market, which increases the potential for decreased local emissions, the use and storage of sustainable energy, and the roll-out and use of electric car-sharing business models. This development also raises new potential issues such as increased electricity …

This handbook brings together scholarship from various subfields, disciplinary traditions, and geographic and geopolitical contexts to understand how student voice is operating in different higher education dimensions and contexts around the world. The handbook helps not only to map the range of student …