Achtergrond: Sedentair gedrag en een lage lichamelijke activiteit kunnen het herstel na een kniearthroplastiek (KA) bij patiënten in de werkzame leeftijd beïnvloeden. Deze hypothesegenererende studie onderzoekt of perioperatieve niveaus van lichamelijke activiteit samenhangen met de tijd tot volledige …

BACKGROUND:  Digitalization in geriatric rehabilitation presents unique challenges, making it essential to align eHealth solutions with patients' digital skills. The Quickscan Digital Skills (QDS) is a tool designed to help healthcare professionals match eHealth interventions to individual skill levels. …

IMPORTANCE: Older patients hospitalized for cardiovascular disease (CVD) are at risk of physical function decline and adverse health outcomes. Cardiac rehabilitation (CR) improves physical functioning but is underutilized by older patients. Home-based CR potentially improves utilization, yet its effectiveness …

Associations between household dysfunction in childhood and school-to-work trajectories throughout young adulthood were examined along with the mediating role of adolescent mental health problems. Data from 1134 participants in the Dutch prospective cohort TRacking Adolescents’ Individual Lives Survey …

Background: Fall prevention programs have been proven effective in reducing falls and fall-related injuries in specific target groups and settings. However, implementing these programs on a larger scale often requires adjustments for feasibility. This study assessed the effectiveness of the nationally …

Objectives Following an anterior cruciate ligament (ACL) injury, athletes may become more reliant on their vision to maintain postural control. Wearing stroboscopic glasses, which intermittently disrupt visual input, can result in decreased vision. However, it remains unclear whether this affects single-leg …

Background: Pain assessment is a necessary step in pain management in older people in palliative care. In older people, pain assessment can be challenging due to underreporting and atypical pain manifestations by other distressing symptoms. Anxiety, fatigue, loss of appetite, nausea, insomnia, dyspnoea, …

BACKGROUND: Sarcopenic obesity (SO) is a clinical condition defined by the coexistence of high body fat mass and low muscle function and mass, which increases the risk of adverse health outcomes, including disability and mortality. Early detection and frequent monitoring of SO are essential for preventive …

Background&aims Obesity and sarcopenia are major health concerns, particularly among older populations. Dietary protein may help preserve muscle mass and function, but high-protein diets, especially from animal sources, may also increase adipose mass. We investigated associations of total, animal, and …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …