Metformin prevents weight gain in patients with type 2 diabetes (T2D). However, the mechanisms involved are still unknown. In this post hoc analysis of the HOME trial, we aimed to determine whether metformin affects energy intake. Patients with T2D were treated with 850 mg metformin or received placebo …

Voor de komende jaren wordt een toename in elektrisch vervoer voorzien. Naast lichte elektrische vrachtvoertuigen betreft het elektrische bestel- en vrachtwagens met een hoger laadvermogen. Het opladen van die elektrische voertuigen betekent een extra belasting voor de elektrische infrastructuur. Gebruikers …

The library of The Hague consists of eighteen buildings, scattered throughout the city. The main building, located in the city center, attracted more than 1.1 million visitors and customers in 2016. The library is part of the municipality of The Hague and the main building is actually integrated within …

The following report aims to introduce the main me2 specifications, and to describe the requirements needed to develop the me2 project. Me2 is a technological platform where the behaviours related to energy consumption could be monitored, and also to increase the energy efficiency. In order to have a …

Background: Patients with chronic obstructive pulmonary disease (COPD) demonstrate reduced levels of daily physical activity (DPA) compared to healthy controls. This results in a higher risk of hospital admission and shorter survival. Performing regular DPA reduces these risks. Objective: To develop …

1. Summary The goal of the graduation thesis is to develop a method to analyze the energy losses through pipe shoe supports. The end result will be an excel file that can be used by any of the engineers within Jacobs. Therefore all calculation and fundamental data must be included. To achieve this goal …

1.1 Techniek verliest talent Verschillende branches in de technische sector kampen met een tekort aan personeel en de verwachting is dat deze tekorten ook in de komende jaren zullen blijven bestaan (ROA, 2013). Om de tekorten op te vangen wordt hard gewerkt aan het motiveren van jongeren om een technische …

Purpose/objective: Stereotactic radiosurgery of brain metastases requires highly conformal dose distributions. Besides beams setup, characteristics of the linear accelerator collimator may also play a role. In this study we compared the impact of leaf width on the dose outside the target for stereotactic …

OBJECTIVES: To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system. METHODS: Twenty HNC patients were enrolled in this in-silico comparative planning …

An estimated 17 million tonnes of tires are discarded annually. Re-use is achieved by retreading (9%), recycling (39%), energy recovery (37%) and landfill (5%). A preferred, but complex way of recycling is to make new tires from discarded tire rubber. Vulcanised car tire rubber has to be devulcanized …