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Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS

Morales-Quinteros, Luis; Neto, Ary Serpa; Artigas, Antonio; Blanch, Lluis; Botta, Michela; Kaufman, David A.; Schultz, Marcus J.; Tsonas, Anissa M.; Paulus, Frederique; Bos, Lieuwe D.

BACKGROUND: Estimates for dead space ventilation have been shown to be independently associated with an increased risk of mortality in the acute respiratory distress syndrome and small case series of COVID-19-related ARDS. METHODS: Secondary analysis from the PRoVENT-COVID study. The PRoVENT-COVID is …

2021AlgemeenArtikel

Cachexia, dietetic consultation, and survival in patients with pancreatic and periampullary cancer: A multicenter cohort study

AEJ Latenstein; WPM Dijksterhuis; TM Mackay; S Beijer; CHJ van Eijck; IHJT de Hingh; IQ Molenaar; MGH van Oijen; HC van Santvoort; Marian de van der Schueren; J de Vos-Geelen; JHM de Vries; JW Wilmink; MG Besselink; HWM van Laarhoven

It is unclear to what extent patients with pancreatic cancer have cachexia and had a dietetic consult for nutritional support. The aim was to assess the prevalence of cachexia, dietitian consultation, and overall survival in these patients. This prospective multicenter cohort study included patients …

2021AlgemeenArtikel

Stratified care integrated with eHealth versus usual primary care physiotherapy in patients with neck and/or shoulder complaints: protocol for a cluster randomized controlled trial.

M.L. van TIlburg; C.J.J. Kloek; M.F. Pisters; Bart Staal; J.M. van Dongen; M. de Weerd; R.W.J.G. Ostelo; N.E. Foster; C. Veenhof

BACKGROUND: Neck and shoulder complaints are common in primary care physiotherapy. These patients experience pain and disability, resulting in high societal costs due to, for example, healthcare use and work absence. Content and intensity of physiotherapy care can be matched to a patient's risk of persistent …

2021AlgemeenArtikel

Cachexia and Dietetic Interventions in Patients With Esophagogastric Cancer: A Multicenter Cohort Study

WPM Dijksterhuis; AEJ Latenstein; JJ van Kleef; RHA Verhoeven; JHM de Vries; M Slingerland; E Steenhagen; J Heisterkamp; LM Timmermans; Marian de van der Schueren; MGH van Oijen; S Beijer; HWM van Laarhoven

Background: Cachexia is common in patients with esophagogastric cancer and is associated with increased mortality. Nutritional screening and dietetic interventions can be helpful in preventing evolvement of cachexia. Our aim was to study the real-world prevalence and prognostic value of pretreatment …

2021AlgemeenArtikel

Perceptions and ideas of critically ill patients, their family and staff members regarding family participation in the physiotherapy-related care of critically ill patients

Lotte van Delft (Onderzoeker); Karin Valkenet (Onderzoeker); Arjen Slooter (Onderzoeker); Cindy Veenhof (Lector)

Background: Involvement of families in physiotherapy-related tasks of critically ill patients could be beneficial for both patients and their family. Before designing an intervention regarding family participation in the physiotherapy-related care of critically ill patients, there is a need to investigate the …

2021GezondheidArtikel

The Impact of Nursing Delirium Preventive Interventions in the ICU. A multicenter cluster-randomized controlled clinical trial

Paul Rood; M. Zegers; D. Ramnarain; M. Koopmans; T. Klarenbeek; E. Ewalds; M. van der Steen; A. Oldenbeuving; M. Kuiper; S. Teerenstra; E. Adang; L.M. van Loon; A. Wassenaar; H. Vermeulen; P. Pickkers; M. van den Boogaard

2021AlgemeenArtikel

PRactice of VENTilation in Patients with Novel Coronavirus Disease (PRoVENT-COVID)

Boers, Noor S.; Botta, Michela; Tsonas, Annisa M.; Algera, Anna Geke; Pillay, Janesh; Dongelmans, Dave A.; Horn, Janneke; Vlaar, Alexander P. J.; Hollmann, Markus W.; Bos, Lieuwe D. J.; Paulus, Frederique (Lectoraat Critical Care); Neto, Ary Serpa; Schultz, Marcus J.

Background: The coronavirus disease 2019 (COVID-19) pandemic is rapidly expanding across the world, with more than 100,000 new cases each day as of end-June 2020. Healthcare workers are struggling to provide the best care for COVID-19 patients. Approaches for invasive ventilation vary widely between …

2020-10AlgemeenArtikel

The longitudinal association between depressive symptoms and functional abilities in older patients

OBJECTIVES: To investigate the course of depressive symptoms, and basic and instrumental activities of daily living (collectively described as, (I)ADL functioning) from acute admission until one year post-discharge, the longitudinal association between depressive symptoms and (I)ADL functioning, and …

2020-10AlgemeenArtikel

Study protocol of a randomized, doubleblind, placebo-controlled, multi-center trial to treat antipsychotic-induced weight gain

Nini de Boer; Sinan Guloksuz; Caroline van Baal; Leonie Willebrands; Jeroen Deenik; Wilma Swildens (Lector)

Abstract Background: Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing type-2 diabetes and readmission. Treatment of AiWG is currently challenging, …

2020-03-08GezondheidBijdrage aan periodiek

Doxepin cream is not effective in reducing itch in burn scar patients

Kwa, K A A; Legemate, C M; Pijpe, A; Meij-de Vries, A; Middelkoop, E; van Baar, M E; Breederveld, R S; Nieuwenhuis, M K (Functional Recovery And Quality Of Life After Burns)

OBJECTIVE: To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream. METHOD: We conducted a multicenter triple-blind randomized clinical placebo-controlled crossover trial in which burn patients ≥18 years with an itch intensity ≥3 …

2020-03-01Gezondheid; …Artikel

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