It is estimated that over 30,000 lesions in the DNA are generated per cell per day. In S-phase, lesions in the DNA can stall replication, which can lead to secondary lesions such as DNA double- strand breaks. The DNA damage tolerance (DDT) network enables replication to be continued in the presence of …

The German sportscar brand Porsche is one of the best-selling sportscar brands in the Netherlands, as stated in a research by the RAI association (2019b). Haaglanden Motorsport is a Porsche specialist, with its focus in maintenance, purchase, sales and additional services connected to Porsche. Over the …

Nissan Motor Co. is a worldwide car manufacturer established in Japan in 1933. Nissan has the slogan ‘innovation that excites’, and many years they have been the leader in a few European car branch markets. Examples are the European market of electric cars and a few C-segment markets. This plan is written …

Currently, 2.1 million children in Ghana and Ivory Coast are exposed to extensive working hours and use of sharp and dangerous tools. Furthermore, these children are unprotected to the use of pesticides and are overstraining their bodies with excessive weight carrying. Various large chocolate producing …

Banks in the Netherlands are involved in Corpore Social Responsibility (CSR). What banks do for Corporate Social Responsibility and how they do it is not always clear. Different motives for Corporate Social Responsibility exist and as an effect, it remains questionable how customers would react to CSR …

This dissertation aimed to investigate how Kruidvat can improve their website to attract more customers. There has been a clear upward trend in online shopping in the Netherlands the past years. In order to gain and/or increase their competitive advantage, companies have to stay up-to-date and meet the customers’ …

The global industrial economy is still predominantly linear, working according to the take-make-waste principle. This has affected the planet to a concerning amount, which is why the European Union signed the Paris Agreement, committing to a 1,5 to 2 degree scenario of global warming. In order to achieve …

The main purpose of this dissertation is to establish which road (ownership or circulation) car tax model is best to reduce CO2 emissions in the European Union. In Europe, climate change and reduction of greenhouse gasses is a concern among the population, as it is seen by the growing Eco activism as …

Tropical forests are under serious pressure and deforestation and forest degradation are taking their toll. The mixed dipterocarp forests of Sarawak are no exception. The importance of sustainable forest management is evident and growth models are a convenient tool to help in determining sustainable …

Wilms tumour suppressor gene (WT1) is essential for normal development of a kidney, it was also discovered as a major controller of mesenchymal-epithelial balance in general development of organs. In this project we use Wt1 and its role in the mesenchymal-epithelial balance to study the mechanism of …