Background Fatness and fitness both influence cardiometabolic risk. Objective The purpose of this study was to investigate whether childhood fatness and increasing fatness from childhood to adolescence are associated with cardiometabolic risk during adolescence and how fitness affects this association. …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

To protect the otter population in the Netherlands, it is important to understand the otter's ecology. Otters have a very high metabolic rate, and they need to eat often. Here for we need to know of what species their diet consists, as this might influence their behaviour and distribution. When we know …

BACKGROUND: Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive drugs. However, prolonged use at a medium or high dose is hampered by side effects of which the metabolic side effects are most evident. Relatively little is known about their effect on gene-expression …

De laatste 10 jaar is het houden van reptielen als huisdier toegenomen. Eén van de meest gerapporteerde welzijnsproblemen is metabolic bone disease (MBD), wat gedeeltelijk veroorzaakt wordt door onjuiste verlichting en voeding. Onderzocht wordt wat de kwaliteit is van het uv B-aanbod bij Nederlandse …

The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use …

This review aims to integrate the present state of knowledge on lactate metabolism in human and mammalian physiology as far as it could be subject to nutritional interventions. An integrated view on the nutritional, metabolic and physiological aspects of lactic acid and lactates might open a perspective …

Op 12 oktober 2007 is de nieuwe Nota Dierenwelzijn van het ministerie van Landbouw,Natuur en visserij (LNV) gepubliceerd. In deze nota staat dat uit recente analyse van de Faculteit Diergeneeskunde Universiteit Utrecht en Wageningen Universiteit dat veel mensen bij de verzorging van hun huisdier vaak …

Physical activity (PA) and physical fitness (PF) are inversely associated with the clustering of cardiovascular disease (CVD) risk factors (RF) associated with the metabolic syndrome (MS). However, the role of individual components of PA, that is, intensity, duration and volume, and the inter-relationship …

That sulfur is essential to humans is based on the requirement of S-animo acids for normal growth and maintenance of nitrogen balance and not on the optimization of metabolic proccesses involving the synthesis of non-protein sulphur containing compounds. This paper reviews the significance of sulfur …