Background Increased protein provision might ameliorate muscle wasting and improve long-term outcomes in critically ill patients. The aim of the PRECISe trial was to assess whether higher enteral protein provision (ie, 2·0 g/kg per day) would improve health-related quality of life and functional outcomes …

Highlights What is the primary question addressed by this study? What is the accuracy of DeltaScan;a portable brain state monitor that offers real-time automated artifact rejection and analysis, delivering a probability score for both acute encephalopathy and delirium in both ICU and non-ICU patients? …

In the past two decades, awareness about traumatic brain injury has been increasing in the public health. Informative and educational programs such as the Concussion Management program from the University of Kansas Health System have been reaching out to education, health and sports facilities. Practical …

Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described. Experimental endotoxemia (2 ng/kg Escherichia coli lipopolysaccharide [LPS]) was induced in 15 subjects, whereas 10 served …